Th. doct.--Paris, 1970. / Notes bibliogr. Bibliogr. p. XIII-XXIX du t. 1.

Thesis (B. A.)--University of Wisconsin -- La Crosse, 2008. / Also available online. Includes bibliographical references (leaves 64-66).

The aim of the thesis is to evaluate the current version of the Integrated Study Information System at the University of Economics with focus on usability. An improved solution is suggested based on latest development in the field. The theoretical part contains selected approaches to redesign of web application. The resulting solution is in a form of redesigned key parts of the information system common to most functions in the student related section. Wireframes and static website mockups are used in order to illustrate the suggested solutions.

Marine natural products which contain a £]- carboline skeleton are widely distributed in marine invertebrates. The discovery of natural £]- carboline metabolites as potent antitumor and antival agents has stimulated a great interest on the synthetic and pharmatological studies of£]- carboline derivatives. Herein, the preparation, charactrization and biolgical evaluation of 1-substituted 1,2,3,4-tetrahydro-£]- carboline and 3,4-dihydro-£]- carboline derivatives are reported. A facile synthetic method by the application of Pictet-Sengler reaction and DDQ oxidation allowed the preparation of compounds 63-72. Compounds 63-67 were synthesized from tryptamine and N-substituted-3-carbazole carboxaldehyde via Pictet-Spengler cyclization. Subsequent oxidation of compounds 63-67 by DDQ furnished compounds 68-72. The structures of compounds 63-67 were determined by several spectroscopic methods. A series of 1-substituted-1,2,3,4-tetrahydro-£]- carboline (63-67) and 3,4-dihydro-£]- carboline derivatives (68-72) have been evaluated to possess cytotoxicity against human tumor cells including KB16, DLD and NCI cell lines. On the other hand, chromatographic separation of acetone extract of Formosan grogonian coral Isis hippuris (collected in Gree island) has led to the isolation of four marine steroids namely hippurin-1 (74), 22-epi-hippurin-1 (80), 2-deacetylhippurin-1 (82) and 2-deacetyl-22-epi-hippurin-1 (83), as well as a new compound 4-hydroxy-5-(p-hydroxy phenyl)-pentane-2, 5-dione (86). The structures of all above compounds were established on the basis of spectral analysis. Biological studies revealed that compounds 74, 80, 82, 83 exhibited potent cytotoxicity against NUGC tumor cells, but compound 86 was inactive.

In our continuing study on the chemical constituents of Taiwanese soft corals, the EtOAc extracts of a gorgonian coral Isis hippuris and a alcyonarian coral Sinularia gibberosa were investigated, respectively. Seven compounds, including 3£\,11£]-dihydroxy-24-methyl-22,25epoxy-5£\- furostan-18,20£]-lactone (1), 3-acetyl-2-deacetyl-22R-hippurin-1 (2), hippuristerone F (3), hippurin-1 (4), 22-epi-hippurin-1 (5), 3-acetyl-2- desacetyl-22-epi-hippurin-1 (6) and 2-desacetyl-22-epi-hippurin-1 (7) were isolated from I. hippuris. Three metabolites, 3£],11-dihydroxy-24- methylene-9,11-secocholest-5-en-9-one (8), 3£],11-dihydroxy-24-methyl-9, 11-secocholest-5-en- 9-one (9) and 3£]-hydroxy-11-acetoxy-24-methylene-9, 11-secocholest-5-en-9-one (10) were isolated from S. gibberosa. Among them, compounds 1¡V3, are new products. All metabolites 1¡V10 are steroids. The structures of 1¡V10 were determined by physical and spectral analysis, including IR, MS, 1D NMR (1H, 13C) and 2D NMR ( 1H-1H COSY, HMQC, HMBC and NOESY ) and by comparison with the related physical and spectral data of the known compounds. The cytotoxicity of the isolates against the P-388 ( mouse lymphocytic leukemia ), A-549 ( human lung adenocarcinoma ) and HT-29 ( human colon adenocarcinoma ) cancer cell lines were studied. Compound 9 and 10 showed significant cytotoxicity against P-388 cancer cell line. Metabolites 6 and 8 showed significant cytotoxicity against P-388 and HT-29 cancer cell lines. Compound 2, 4 and 5 exhibited potent cytotoxicity against the growth of P-388, A-549 and HT-29 cancer cell lines.

Since events of September 11 and the subsequent conflicts surrounding the event, the war against terrorism has been constantly present. It has been used several methods and strategies to address these threats, including a method current in use, the targeting method. The method refers to use few but precise attacks to knock out key functions within these organizations, mostly individuals in the higher command and control structures within these organizations. The effectiveness of the method has been put in question when the majority of the terrorist organizations continue their strife, in some cases even increasing its intensity. The purpose of this study is to investigate which role the higher command plays in these organizations ability to wage war. This study utilize the organization ISIS as a representative for other similar Islamist terrorist organizations. The study use theories regarding network based groups and decentralized organizations in order to explain the structure of ISIS. The study shows that ISIS is an organization which has largely evolved into something other than what is described as an typical terrorist organization, the organization is more like one among other nations with a large and well structured organization, where management conditions are clear and well developed. ISIS can be a inconsistency in terrorist organizations, but may also have developed like the theoretician Galula named as the fourth step in the orthodox model of an terrorist or irregular force inevitable development  in the struggle for control.

Thesis (M.A.)--Cincinnati Christian University, 2005. / Abstract and vita. Includes bibliographical references (leaves 177-190).

Texte remanié de: Doct. Th.--Los Angeles--University of California, 1992. Titre de soutenance : Roman politics and the cult of Isis and Sarapis. / Bibliogr. pp. [207]-230. Index.

Thesis (M.A.)--Cincinnati Christian University, 2005. / Abstract and vita. Includes bibliographical references (leaves 177-190).

Thesis (doctoral)--In Universitate Lugduno-Batava, 1900. / Includes bibliography.