The thesis is focused on CNC machines. The theoretical part describes the historical development of CNC machines. A substantial part is devoted to CNC machine construction description. The elementary principles of CNC machine programming and NC code formation are described. There is a research of small commercially available CNC milling machines. Practical part deals with design and construction of small three axis CNC milling machine. Set of samples is machined for analysis of CNC router dimensional accuracy. CNC milling precision is evaluated in the end of the thesis. Recommended operating parameters machine improvement and modification possibilities are described.

Tato práce řeší vysokou fluktuaci zaměstnanců ve firmě a analyzuje její příčiny, dále doprovodné jevy jako neudržení know-how ve firmě či důsledky jejího růstu. Dalším tématem této práce je analýza přijímacího řízení. Výzkum je prováděn na malém podniku, jehož hlavním předmětem podnikání je developerská činnost na zakázku v oboru IT/ICT. Unikátnost této práce spočívá především v možnosti použití kromě jiných metod i techniky skrytého pozorování.

Both pronuclei of the zygote undergo epigenetic changes after fertilization, which determines the quality of the zygote and successful early mammalian embryonic development. Shortly after fertilization epigenetic asymmetry among the pronuclei of the zygote is evident, while the paternal pronucleus undergoes active DNA demethylation, the DNA of the maternal pronucleus remains methylated. The male pronucleus in addition undergoes histone acetylation, whereas the histones of the female pronucleus remain methylated. Asymmetry of pronuclei and their epigenetic status predicts successful reprogramming of the genome, and thus the success of embryonic development. For the successful development of the embryo is therefore required correct formation of both of these pronuclei of the zygote and this formation of pronuclei is regulated by post-translational histone modifications called histone code. It was hypothesized that the histone code is regulated by the activity of NADP+ - dependent histone deacetylases, sirtuins. In the experiment were used fully grown in vitro maturated pig oocytes that were fertilized with pig spermatozoa in vitro. After isolation of zygotes cultured with addition of the activator sirtuin resveratrol was performed immunofluorescence analysis of acetylated and methylated histone H3 at lysine K9 of pronuclei of the zygotes. From the results of control group asymmetry between the pronuclei of the zygote is evident; wherein the male pronucleus exhibits higher acetylation intensity contrast female pronucleus exhibits higher methylation intensity. After adding resveratrol to all experimental groups female pronucleus showed a significant increase of the methylated histone H3 at lysine K9, and contrary to the male pronucleus significant decrease of acetylated histone H3 at lysine K9. Sirtuins are involved in the regulation of histone code in porcine zygote and it can be assumed that they also play a role during subsequent embryonic development, which is the subject of further study.

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This work deals with forward error correction. In the work, basic methods and algorithms of error correction are described. For the presentation of encoding and decoding process of Hamming code, Reed-Müller code, Fire code, Reed-Solomon code and Trellis coded modulation programs in Matlab were created.

Main goal of this thesis is to create disassembler for Visual Basic 6 binary .exe files. There is description of Portable Executable files, description of disassembler, as well as functions of Windows API calls. Visual Basic disassembler should provide as much information about Visual Basic 6 file as possible. There is detailed structure specification of Visual Basic 6 binary files.

This work deals with problems of the barcode applied to automatic identification. Description of their major part, creation of the bar code online generator, a web-page information system using the barcodes to identify the object, is presented.

The goal of this thesis is to describe barcodes used in real world applications and to create application for real time detecting and decoding of chosen barcodes using computer vision. Normal linear barcode is first introduced, and then two dimensional matrix barcode is described with focus on its origin, usage and structure. Especially the process of localization, encoding and decoding of QR Code, which is chosen for future use in work, is described mainly. Also briefly description of computer vision and OpenCV library is available. Next the concept and implementation of application for localization and recognition of QR Codes is described. Finally description of testing, evaluation of thesis and ways of improvements are discussed.

Code generation from UML is still very limited. Diagrams, which are usually used for code generation describes the static structure. These are mostly the class diagrams. One of the most useful and least used types of diagrams is behavioral diagrams. The reason for this is mainly a lack of support from the UML specification. The onset of version 2.0 has brought visible changes in this area. This thesis will focus only on activity diagrams and possibilities of code generation from them. One of them will be verified on a prototype tool that can generate skeleton of code in chosen language (e.g. Java, C + +, PHP ,...). Then it will be compared to alternative approaches and evaluated in terms of its advantages and disadvantages. As input is expected activity diagram created and exported by external CASE tool in XMI format. Architecture of tool will provide possibility of defining new modules. So the end user will be able to program another output language by the medium of given interface.