No description available.

No description available.

No description available.

The aim of this thesis was to assess whether platelet, endothelial and coagulation biomarkers of thrombotic risk are increased in ECKD-HD patients. Five individual studies were performed (1) venous blood samples between controls and resting HD patients, (2) simultaneous blood samples between vascular access (VA) and venous samples in HD patients (3) pre and post dialysis from the VA, (4) samples pre and post dialysis in venous samples, (5) a retrospective study of VA thrombosis in HD patients. Venous blood samples were taken from 78 resting healthy volunteers and from 78 HD patients immediately before and 30 minutes after dialysis. We also took blood samples from the VA of 55 patients immediately before and after dialysis. In 26 patients venous and VA samples were taken simultaneously. Our results have shown HD patients potentially have evidence of a prothrombotic state compared to controls. This is further increased by each session of dialysis and is present in both VA and venous samples distant from the site of haemodialysis. We have shown some differences in platelet activation and inflammatory markers between simultaneous VA and venous samples. Furthermore, some of these biomarkers may be associated with a retrospective history of VA occlusion. Our study has shown that in patients with ECKD on HD there may be evidence of an underlying prothrombotic tendency. There is a need to determine the optimal anti-platelet and anti-coagulation therapy in these patients.

by Tse Kam Wah. / "September 1998." / Thesis (Ph.D.)--Chinese University of Hong Kong, 1998. / Includes bibliographical references (p. 123-145). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

Fung Kwai Ching. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1997. / Includes bibliographical references (leaves i-ix (last gp.)). / Acknowledgement --- p.i / Legend for graphs --- p.ii-iii / Legend for pictures --- p.iv / Legend for diagrams --- p.v / Legend for tables --- p.vi / Abstract --- p.vii-viii / Introduction --- p.1-17 / Chapter 1 --- Known Anatomy and Physiology --- p.1-2 / Chapter 2 --- The Nephron --- p.3-4 / Chapter 3 --- Renal Vasculature --- p.5-7 / Chapter 4 --- Summary of renal anatomy from infancy to children from review of literature --- p.8 / Chapter 5 --- Function of the kidney --- p.9-17 / Imaging Background --- p.18-23 / Chapter 1 --- Neonates and infants kidneys- sonographic appearance of echogenicity --- p.18-19 / Chapter 2 --- Prominence of medullary pyramicd (MP) --- p.20-21 / Chapter 3 --- Morphometric Studies --- p.22-23 / Aim of Study --- p.24 / Method --- p.24-41 / Chapter 1 --- Method --- p.24-30 / Chapter 2 --- """Limitations"" to the technique" --- p.30-34 / Chapter 3 --- Establishing the technique --- p.35-41 / Results --- p.42-62 / Chapter 1 --- Comparison of kidney length with age --- p.42-44 / Chapter 2 --- Corticomedullary and age relationship --- p.45-48 / Chapter 3 --- Medullary thickness correlated with age --- p.48-52 / Chapter 4 --- Sum of the cortical thickness and medullary thickness versus kidney length --- p.53-54 / Chapter 5 --- Compare CMR with kidney length and --- p.55-56 / Chapter 6 --- CMR versus age --- p.57-59 / Chapter 7 --- Mean of CMR related to age group --- p.57-59 / Chapter 8 --- Compare CMR with kidney length and age --- p.60 / Chapter 9 --- Compare gender and CMR --- p.60-61 / Chapter 10 --- Compare laterality and CMR --- p.60 / Result summary --- p.62 / Discussion --- p.63-84 / Chapter 1 --- Cortex --- p.63-65 / Chapter 1.1 --- Cortex: anatomy --- p.66-67 / Chapter 1.2 --- Cortex: physiology --- p.67-76 / Chapter 2 --- Medulla --- p.76-81 / Chapter 2.1 --- Medulla: anatomy --- p.76 / Chapter 2.2 --- Medulla: physiology --- p.76-81 / Chapter 3 --- "Corticomedullary ratio, CMR" --- p.82-83 / Chapter 4 --- CMR and Kidney Length --- p.83 / Chapter 5 --- "The CMR, Kidney Length and Age" --- p.83 / Chapter 6 --- Corticomedullary Ratio and its relationship to actual corticomedullary volume ratio --- p.84 / Chapter 7 --- "Laterality, Sex of the subjects" --- p.84 / Implications --- p.84-94 / Clinical pathological cases and corticomedullary ratio CMR --- p.90-94 / Conclusion --- p.94-95 / Appendix --- p.96-103 / Chapter 1 --- Morphologic Development and Anatomy of the Kidneys and Urinary Tract --- p.96-98 / Chapter 2 --- Renal Perfusion and Glomerular Filtration --- p.99-101 / Chapter 3 --- Classification of renal diseases --- p.102-103 / References

Thesis (Ph.D.) -- University of Texas at Arlington, 2008.

published_or_final_version / Pathology / Master / Master of Philosophy

No description available.

Thesis (doctoral)--Lund University, 1997. / Added t.p. with thesis statement inserted.