The study has intended to analyze the Europeanization of the institutional structure for regional policy in Bulgaria after the first programming period of the country as a full-fledged member state of the EU. Bulgaria joined the EU in 2007 as part of the so called ‘Eastern Enlargement’ that was characterized by power asymmetry and strong conditionality. The study employs two research methods – document analysis of key policy documents and legislation, as well as qualitative interviews with key respondents with involvement or experience in the field of regional policy and development in Bulgaria. The analysis is underpinned by the concept of Europeanization and historical institutionalism which complement each other in order to explain the changes and the reasons for them. The main findings show that the EU requirements are only ‘accommodated’ in the already existing institutional structure of Bulgaria and real transformation has not occurred. The established regional level still does not have a significant role in the regional policy of the country because it represents neither self-government, nor administrative unit. The research suggests directions for future reform and refinement of the current institutional system with regard to the better formulation and implementation of regional policy in the country.