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Validation et exploitation d’un registre histologique des cancers : Estimation par capture recapture de l’exhaustivité par modélisation log-linéaire et selon les modèles écologiques Mtbh en Bayesien / Assessing the value of a histopathological cancer registry : Completeness estimation by capture-recapture by log-linear modeling and on ecological models Mtbh in BayesianBailly, Laurent 08 December 2011 (has links)
Introduction: Les études populationnelles sur le cancer nécessitent un recensement de référence fiable et exhaustif, en théorie possible à partir d'un recueil histologique. Méthode: Depuis 2005, toutes les structures d'anatomopathologie des Alpes-Maritimes adressent les codes ADICAP des tumeurs malignes et invasives et identifiants patients. L'exhaustivité pour les cancers du sein et colorectaux des 50-75 ans a été évalué par méthode de capture recapture en modélisation log-linéaire et en Bayesien à partir des cas communs ou non dépistés et vus en Réunion de Concertation Pluridisciplinaire. RésultatUn programme d'assurance qualité a permis de s'assurer de la fiabilité des données recueillies.L'estimation de l'exhaustivité était de plus de 90 % pour les cancers du sein et colorectaux des 50-75 ans. Les taux observés sur le département des Alpes-Maritimes, comparés aux taux estimés en France, se sont révélés cohérents.Enfin, la base a été utilisée pour déterminer l'existant les lésions prénéoplasiques du col de l'utérus avant la vaccination anti-HPV. ConclusionCe travail conclut à l'intérêt d'un recueil histologique des cas de cancers incidents. / Introduction Cancer population studies require reliable and complete baseline data, which should theoretically be available by collecting histopathology records.Method Since 2005, all histopathology laboratories from Alpes-Maritimes address ADICAP codes for invasive cancer and patient identifiers. The completeness of such a collection was evaluated using capture-recapture analysis based on three data sources concerning breast and colorectal cancers with the number of cases which were common or not between sources recording screened, diagnosed and treated cancers in the French Alpes Maritimes districtResult Data quality for the ADICAP code database may be considered satisfactoryThe estimated completeness of cancer records collected from histopathology laboratories was higher than 90%.Rates observed in the Alpes-Maritimes, compared with estimated rates in France have proven consistent. Rates of CIN for the entire female population of the Alpes-Maritimes in 2006 has been established.Conclusion A verified and validated histopathology data collection may be useful for cancer population studies.
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Models and Graphics in the Analysis of Categorical Variables: The Case of the Youth Tobacco Survey.Hosler, Deborah Susan 16 August 2002 (has links) (PDF)
Youth Tobacco Surveys have been conducted in several states in the U.S. in recent years, in order to design policies with the goal of reducing tobacco use among young people. Some primary analysis of those surveys has been done, but few analyses include modeling, and the study of independence has been addressed, mainly, in the bivariate context.
In this work contemporary methods, which are of relative recent appearance in categorical data analysis, will be examined, including logistic and log-linear modeling as well as graphical displays and correspondence analysis. These methods will be applied to data from the 2000 Tennessee Youth Tobacco Survey.
The objective is to demonstrate that methods of multivariate categorical data analysis can provide fresh insight about the behavior of adolescents with respect to tobacco use. The ultimate purpose of this work is to recommend methodology that goes beyond that which is currently published.
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