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The impact of lower limb amputation on quality of life: a study done in the Johannesburg Metropolitan area, South AfricaGodlwana, Lonwabo L. 29 January 2010 (has links)
Thesis (M.Sc.(Physiotherapy)), Faculty of Health Sciences, University of the Witwatersrand, 2009 / Background: The impact of non-traumatic lower limb amputation on participant’s
quality of life (QOL) is unknown. In an effort to provide better care for people with
lower limb amputation, there is a need to first know the impact of this body
changing operation on people’s quality of life.
Aim of the study: To determine the impact of lower limb amputation on QOL in
people in the Johannesburg metropolitan area during their reintegration to their
society/community of origin.
Objectives:
1. To establish the pre-operative and post-operative:
QOL of participants (including the feelings, experiences and impact
of lower limb amputation during the time when they have returned
home and to the community).
The functional status of participants.
Household economic and social status of these participants.
2. To establish factors influencing QOL.
Methods: A longitudinal pre (amputation) test –post (amputation) test study
utilized a combination of interviews to collect quantitative data and in-depth semistructured
interviews to gather qualitative data. Consecutive sampling was used
to draw participants (n=73) for the interviews at the study sites pre-operatively.
The three study sites were Chris Hani Baragwanath Hospital, Charlotte Maxeke
Johannesburg General Hospital and Helen Joseph Hospital. Participants were
then followed up three months later for post-operative interviews and key
informants were selected for in-depth interviews (n=12).
Inclusion criteria: Participants were included if they were scheduled for first
time unilateral (or bilateral amputation done at the same time) lower limb
amputation. The participants were between the ages of 36-71 years.
Exclusion criteria: Participants who had an amputation as a result of traumatic
or congenital birth defects were excluded from the study. Participants with comorbidities
that interfered with function pre-operatively were not included.
Procedures:
Ethics: Ethical clearance was obtained from the Committee for Research on
Human Subjects at the University of the Witwatersrand and permission was
obtained from the above hospitals. Participants gave consent before taking part
in the study.
Instrumentation: A demographic questionnaire, the EQ-5D, the Modified
Household Economic and Social Status Index (HESSI), the Barthel Index (BI)
and semi-structured in-depth interviews were used.
Data collection: Participants were approached before the operation for their preoperative
interviews using the above questionnaires and then followed up postoperatively
using the same questionnaires and some were selected to participate
in semi-structured in-depth interviews three months later.
Pilot study: The demographics questionnaire and the modified HESSI were
piloted to ensure validity and reliability.
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Data analysis: Data were analyzed using the SPSS Version 17.0 and STATA
10.0. The significance of the study was set at p=0.05. All continuous data are
presented as means, medians, standard deviations and confidence intervals (CI
95%). Categorical data are presented as frequencies. Pre and post operative
differences were analyzed using Wilcoxon Signed-rank test. A median regression
analysis (both the univariate and multivariate regression) was done to establish
factors influencing QOL. Pre and post operative differences in the EQ-5D items
and the BI items were analyzed using Chi square/Fischer’s exact depending on
the data. Data were pooled for presentation as statistical figures in tables. Both
an intension to treat analysis and per protocol analysis were used.
A grounded theory approach was used to analyze the concepts, categories and
themes that emerged in the qualitative data.
Results: Twenty-four participants (33%) had died by the time of follow up. At
three months, n=9 (12%) had been lost to follow up and 40(55%) was
successfully followed up. The preoperative median VAS was 60 (n=40). The
postoperative median VAS was 70. The EQ-5D items on mobility and usual
activities were reported as having deteriorated significantly postoperatively
(p=0.04, p=0.001respectively) while pain/discomfort had improved (p=0.003).
There was no improvement in QOL median VAS from the preoperative status to
three months postoperatively
The preoperative median total BI score was (n=40). The postoperative median
total BI score was 19. There was a reduction in function (median BI) from the
preoperative status to three months postoperatively (p<0.001).
The ability to transfer was improved three months postoperatively (p=0.04).
Participants were also found to have a decreased ability to negotiate stairs
(p<0.001). Mobility was significantly reduced three months postoperatively
(p=0.04).
During the postoperative stage (n=40), 38% of the participants were married.
Most (53%) of the participants had no form of income. The highest percentage of
participants in all instances (35%) had secondary education (grade10-11), while
25% had less than grade 5. Only one participant was homeless, 18% lived in
shacks, 55% lived in homes that were not shared with other families.
People with LLA in the Johannesburg metropolitan area who had no problem
with mobility preoperatively (EQ-5D mobility item), who were independent with
mobility (BI mobility item) preoperatively, who were independent with transfer
preoperatively (BI transfer item) had a higher postoperative quality of life
(postoperative median EQ-5D- VAS) compared to people who were dependent
or had problems with these functions preoperatively. Being females was a
predictor of higher reported quality of life compared to being male.
Emerging themes from the qualitative data were psychological, social and
religious themes. Suicidal thoughts, dependence, poor acceptance, public
perception about body image, phantom limb related falls and hoping to get a
prosthesis were reported. Some reported poor social involvement due to mobility problems, employment concerns, while families and friends were found to be
supportive. Participants had faith in God.
Conclusion: Participants’ QOL and function were generally scored high both
preoperatively and postoperatively but there was a significant improvement in
QOL and a significant reduction in function after three months although
participants were generally still functionally independent. Good mobility
preoperatively is a predictor of good QOL postoperatively compared to people
with a poor preoperative mobility status
Generally, most participants had come to terms with the amputation and were
managing well while some expressed that they were struggling with reintegration
to their community of origin three months postoperatively with both functional and
psychosocial challenges.
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Participation restrictions and vocational needs amongst persons with a lower limb amputation in Cape Town, South AfricaWing, Yu Tak January 2017 (has links)
Masters of Science - Msc (Physiotherapy) / Vocational rehabilitation relates to rehabilitating a person with an amputation back into actively
participating in society. Although vocational rehabilitation is important, before it can be
implemented, the participation restrictions should be identified. Even though lower limb
amputation surgery is commonly performed in South Africa, and given the high unemployment
rate in the country, no research has been done into the participation restrictions and vocational
needs of a person with a unilateral lower limb amputation in the Western Cape. The aim of this
study was to determine and explore the participation restrictions and vocational rehabilitation
needs in terms of hobbies, sport activities, employment and employment needs of persons with
a unilateral lower limb amputation (LLA) in the Western Cape. The objectives were to: 1)
Determine the participation restrictions of persons with a unilateral LLA in the Western Cape.
2) To explore the vocational rehabilitation needs of persons with a lower limb amputation. A
mixed methods approach, and an explanatory sequential design was used in this study. The
study was conducted in two phases. The first phase utilised a quantitative approach and the
WHODAS 2.0 was used as the instrument to collect data. The second phase aimed to explain
the data collected in the first phase in more depth, and semi-structured telephonic interviews
were utilized to collect the qualitative data. The study was set in the Cape Metropole region of
the Western Cape. Participants were recruited from Tygerberg Tertiary Hospital and a private
sub-acute rehabilitation centre. In the quantitative (first) phase of the study, 50 participants were
conveniently recruited to participate. In the second phase eight participants were purposefully
selected from the pool of 50 participants from the first phase of the study who consented to
participate in the second phase. Quantitative data was analysed using SPSS vs. 22 and analysed
for descriptive and inferential statistics. Qualitative data has been analysed using Creswell's
seven step process of thematic analysis. Ethical clearance has been obtained from the University
of the Western Cape, permission to access patients' details has been obtained from Tygerberg
Tertiary Hospital and private sub-acute rehabilitation centre. Written informed consent as well
as permission for audio recording during the telephonic interview was obtained.
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A Wireless Telemetry System to Monitor Gait in Patients with Lower-Limb AmputationFan, Richard E., Wottawa, Christopher R., Wyatt, Marilynn P., Sander, Todd C., Culjat, Martin O., Culjat, Martin O. 10 1900 (has links)
ITC/USA 2009 Conference Proceedings / The Forty-Fifth Annual International Telemetering Conference and Technical Exhibition / October 26-29, 2009 / Riviera Hotel & Convention Center, Las Vegas, Nevada / Even after rehabilitation, patients with lower-limb amputation may continue to exhibit suboptimal gait. A wireless telemetry system, featuring force sensors, accelerometers, control electronics and a Bluetooth transmission module was developed to measure plantar pressure information and remotely monitor patient mobility. Plantar pressure characterization studies were performed to determine the optimal sensor placement. Finally, the wireless telemetry system was integrated with a previously developed haptic feedback system in order to allow remote monitoring of patient mobility during haptic system validation trials.
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Community experiences of persons with lower limb amputations in MalawiMpezeni, Stella January 2018 (has links)
>Magister Scientiae - MSc / Persons with lower limb amputations (LLA) experience different challenges in the community. These challenges include the physical, psychological and social function of an individual. Little is known in Malawi on what persons with lower limb amputations go through in the communities where they live. Therefore, the study aimed at exploring and determining community experiences of persons with LLA in Malawi. The study sought to address the following objectives: 1) To determine the functional and psychological status of persons with LLA in the community; 2) To explore and describe experiences on social participation of persons with LLA in the community; 3). To explore experiences on community re-integration following LLA.
A mixed method approach was applied where quantitative and qualitative data were collected simultaneously to provide a more holistic overview of the experiences of persons with LLA at one point in time. The study setting was Queen Elizabeth Central Hospital (QECH) and Kamuzu Central Hospitals (KCH) (500 miles), located in Malawi. A sample of 180 participants was recruited to participate in the study. Three self-administered questionnaires (socio-demographic questionnaire, OPUS module of lower extremity functional status, and a Beck’s depression inventory scale) and a semi-structured interview guide were used for data collection. Thematic data analysis was used to analyze qualitative data, while quantitative data was analyzed using descriptive and inferential statistics. Ethical clearance was obtained from the University of the Western Cape Biomedical Research Ethics Committee (BMREC) and College of Medicine Research Ethics Committee (COMREC). Permission to conduct the study was obtained from KCH (500 miles) and QECH. Privacy andconfidentiality was strictly observed such that data obtained was anonymous. It was kept in a secure place, and electronic data was secured using a password.
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Description and evaluation of the rehabilitation programme for persons with lower limb amputations at Elangeni, Paarl, South AfricaFredericks, Jerome P. 03 1900 (has links)
Thesis (MScMedSc)--Stellenbosch University, 2012. / ENGLISH ABSTRACT: Lower limb amputations cause multiple physical, psychological, environmental and socioeconomic
barriers. Individuals who have suffered a lower limb amputation require
comprehensive rehabilitation to ensure social integration and economic self-sufficiency. In
addition, constant monitoring and evaluation is an essential part of human service delivery
programmes. However, the amputation rehabilitation programme offered at Elangeni an outpatient
rehabilitation centre for clients with physical disabilities in Paarl, Western Cape, South
Africa is not monitored, and has not been evaluated since its inception in 2000. Thus, the
current study evolved to describe and evaluate the rehabilitation programme for persons with
lower limb amputations at Elangeni.
A mixed method descriptive design was implemented. All persons who received
rehabilitation, after a major lower limb amputation at Elangeni, between 2000 to 2011, were
included in the study population. In addition, the physiotherapist and occupational therapist
that provided amputation rehabilitation at Elangeni, at the time of the study, were interviewed.
Thirty participants who met the study inclusion criteria were identified. Quantitative data was
collected using a researcher designed, structured demographic questionnaire, an
International Classification of Function checklist based questionnaire and a participant
rehabilitation folder audit form. Two interview schedules one for clients and one for therapists
were used for guidance during semi structured interviews. Quantitative data was entered
onto a spread sheet and analysed by a statistician using Statistica, version 8. Qualitative data
was thematically analysed according to predetermined themes.
No programme vision, mission or objectives could be identified for the amputation
rehabilitation programme. Poor record keeping practices and a lack of statistics were found.
Rehabilitation was impairment focused with no attention given to social integration. Clients
who received prosthetic rehabilitation showed improved functional ability with regard to
picking up objects from the floor (p = 0.031) getting up from the floor (p = 0.00069), getting
out of the house (p = 0.023), going up and down stairs with a handrail (p = 0.037) and moving
around in the yard (p = 0.0069), climbing stairs without a handrail (p = 0.037), going up and
down a kerb (p = 0.0082) walking or propelling a wheelchair more than 1km (0.0089) and
walking in inclement weather (0.017). A lack of indoor mobility training had a statistically significant negative impact on the
participants’ ability to lift and carry objects (p 0.011), standing up from sitting (p = 0.042),
getting around inside the house (p = 0.00023), picking up objects from the floor (p = 0.00068),
getting up from the floor (p = 0.0072), getting out of the house (p = 0.0016), going up and
down stairs with a handrail (p = 0.019), moving around in the yard (0.0013), going up and
down stairs with-out a hand-rail (p = 0.019), getting up and down a kerb (p = 0.0022), walking
or wheeling 1km or more (p = 0.0032) and using transport (p = 0.0034). Failure to address
community mobility during rehabilitation had a statistically significant negative impact on all
aspects of community mobility scores except doing transfers and driving.
In conclusion, for the study participants, Elangeni failed to provide rehabilitation according to
the social model of disability and Community Based Rehabilitation principles. It is
recommended that managers, service providers, and clients re-consider the purpose of
Elangeni and develop a vision and objectives for that service. In addition, management
should take an active role in service monitoring and evaluation and provide guidance and
mentorship to therapists. / AFRIKAANSE OPSOMMING: Onderste ledemate amputasies impak negatief op `n persoon se fisiese, sielkundige en
sosiale funksionering. Individue wat ’n amputasie ondergaan het benodig omvattende
rehabilitasie om sosiale integrasie en ekonomiese onafhanklikheid te verseker. Konstante
monitering en evaluasie is ’n essensiële deel van rehabilitasie programme. Nietemin die
amputasie rehabilitasie program wat by Elangeni aangebied word, word nie gemoniteer nie
en was nog nooit geëvalueer nie. Dus het hierdie studie dit ten doel om die rehabilitasie
programme vir persone met onderste ledemate amputasies by Elangeni te beskryf en te
evalueer.
Kwantitatiewe en kwalitatiewe navorsingsmetodes is in kombinasie gebruik in die studie. Alle
persone wat rehabilitasie by Elangeni ontvang het na ’n onderste ledemaat amputasie, sowel
as die terapeute wat by Elangeni werk, het die studie populasie gevorm. In totaal het 32
persone aan die studie deelgeneem. Kwantitatiewe data is met behulp van `ʼn demografiese
vraelys, `ʼn ICF gebaseerde vraelys, en `ʼn leer oudit vorm ingesamel. Twee onderhoud
skedules, een vir die kliënte en een vir die terapeute, is gebruik as riglyn tydens insameling
van kwalitatiewe data. Kwantitatiewe data is statisties ontleed deur ʼn statistikus wat gebruik
gemaak het van Statistica 8. Voorafbepaalde temas is gebruik tydens tematies ontleding van
kwalitatiewe data.
Geen program visie, missie of doelwitte kon geïdentifiseer word nie. Swak rekord houdings
praktyke was gevind. Rehabilitasie het gefokus op die fisiese en nie op sosiale integrasie nie.
Die kliënte wat prostetiese rehabilitasie ontvang het, het statisties beduidend beter gevaar
ten opsigte van optel van voorwerpe van die vloer af (p = 0.031), om van die vloer af op te
staan (p = 0.00069), om uit die huis uit te kom (p = 0.023), om trappe met `ʼn handreling te
klim (p = 0.037), om op die erf rond te beweeg (p = 0.0069), om trappe sonder `ʼn reling te
klim (p = 0.037), om by sypaadjies op en af te gaan (p = 0.0082), om meer as `ʼn kilometer te
loop of met die rolstoele te ry (0.0089) en om in ongure weer te loop (0.017).
`ʼn Tekort aan heropleiding van mobiliteit binne die huis het `ʼn statisties beduidende impak
gehad op die vermoë om goed te dra (p 0.011), op te staan van sit af (p = 0.042), in die huis
rond te beweeg (p = 0.00023), voorwerpe van die vloer af op te tel (p = 0.00068), van die
vloer af op te staan (p = 0.0072), uit die huis uit te kom (p = 0.0016), trappe met `ʼn handreling te klim (p = 0.019), in die erf rond te beweeg (0.0013), trappe sonder `ʼn handreling te klim (p
= 0.019), by `n sypaadjie op en af te gaan (p = 0.0022), meer as 1km te loop of met die
rystoel te ry (p = 0.0032) en om vervoer te gebruik (p = 0.0034). `ʼn Gebrek aan heropleiding
van gemeenskapsmobiliteit het `ʼn statisties negatiewe impak gehad op alle aspekte van
gemeenskapsintegrasie behalwe die doen van oorplasings en bestuur.
Rehabilitasie praktyke was nie gebaseer op die sosiale model van gestremdheid en
Gemeenskap Gebaseerde Rehabilitasie beginsels nie. Dit word aanbeveel dat diens
verskaffers, kliënte en bestuurders oor die fokus van rehabilitasie by Elangeni moet besin.
Daar moet ʼn visie en doelwitte vir die diens ontwikkel word. Voorts moet bestuurders van
distrik vlak ʼn aktiewe rol speel in die monitering en evaluasie van dienste en mentorskap aan
terapeute verseker.
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Imagerie motrice et amputation du membre inférieur / Motor Imagery and Lower-Limb AmputationSaruco, Elodie 21 November 2017 (has links)
L'imagerie motrice, ou représentation interne d'un mouvement, est une technique d'entraînement mental ayant la particularité d'impacter la plasticité cérébrale activité-dépendante. La pertinence de son intégration au sein des programmes de rééducation fonctionnelle a été validée par de nombreuses études expérimentales, tout particulièrement pour les personnes victimes d'un accident vasculaire cérébral ou d'une lésion de la moelle épinière. Les résultats obtenus par ce travail de thèse élargissent l'éventail des populations pouvant bénéficier de cette approche en validant la faisabilité et en précisant les conditions optimales de l'intégration de l'imagerie motrice dans le cadre de la rééducation de personnes amputées du membre inférieur. Nous rapportons également des résultats préliminaires prometteurs quant à ses effets sur le recouvrement de leurs capacités locomotrices. Les données montrent que le travail en imagerie motrice devrait être spécifique aux mouvements fonctionnels bilatéraux et que, sous réserve d'une prochaine validation auprès de cette population, l'imagerie motrice de tâches posturales ainsi que l'utilisation conjointe de la stimulation transcrânienne à courant continu, devraient permettre de maximiser son pouvoir d'action sur le recouvrement de la locomotion de personnes amputées du membre inférieur / Motor imagery, which refers to the internal representation of a movement, has the potential to impact activity-dependent plasticity. The relevance of motor imagery, as a technique allowing substantial motor performance gains and motor recovery in the field of rehabilitation, has been validated by numerous experimental studies in stroke patients and persons suffering from spinal cord injury. By highlighting the possibility of integrating motor imagery within the framework of lower-limb amputees’ rehabilitation programs, and revealing promising preliminary data regarding locomotion recovery, the results of this thesis broaden the range of people which might benefit from this technique. Data further suggest that motor imagery should specifically focus on functional and bilateral tasks, and that concomitant use of transcranial direct current stimulation should contribute to potentiate the impact of motor imagery on locomotion recovery of lower-limb amputees
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Vers une approche multidimensionnelle de l'évaluation motrice du sujet amputéSagawa, Yoshimasa 29 May 2012 (has links)
Les personnes amputées de membre inférieur (PAMI) sont très diversifiées. Ils’agit d’une population hétérogène, tant par ses origines que par ses niveaux d’amputation, ses capacités et ses projets de vie. A ces profils variés s’ajoutent une multitude de composants prothétiques ainsi que les différentes combinaisons possibles entre ces composants. Il est également important de prendre en compte les différents environnements auxquels la PAMI est confrontée quotidiennement. La Classification Internationale du Fonctionnement (CIF 2001) a été créée par l’Organisation Mondiale de la Santé et repose sur un modèle multidimensionnel. Elle est constituée de deux grandes parties : le fonctionnement d’une part et les facteurs contextuels d’autre part. Ce modèle est capable de décrire de manière globale les modifications de fonctionnement (handicap) à partir d’un problème de santé quelconque. Ainsi, une grande quantité d’informations peut être obtenues à partir du modèle de la CIF. Néanmoins, il demeure nécessaire de développer de nouveaux outils pour mieux exploiter ce modèle afin de le rendre plus intelligible et utilisable en pratique clinique courante. Pour cela, nous nous proposons d’utiliser l’Extraction de Connaissances à partir des Données (ECD). L’ECD est un processus non trivial d'identification des structures inconnues, valide et potentiellement exploitable dans les bases de données, qui permet de transformer un maximum d’informations en connaissances facilement exploitables. A partir du modèle de la CIF et conjointement avec des méthodes d’ECD, l’objectif de cette thèse est de caractériser un groupe de PAMI expertes en termes de capacités locomotrices. Ce groupe et sa liste d’indicateurs pertinents reposant sur le modèle de la CIF ont été déterminés. Ils servent de référence pour la comparaison d’autres PAMI et peuvent guider la prise en charge de cette population particulière. / The subjects with a lower-limb amputation (LLA) compose a heterogeneouspopulation, by their amputation origins, by their amputation levels, by their abilities and by their life projects. To these various LLA’s profiles we could add a multitude of prosthetic components and the combination of these components. It is also important to take into account the different environments, which the LAA are confronted daily. The International Classification of Functioning, Disability and Health (ICF 2001) was created by the Word Heath Organization and is based on a multidimensional model. The ICF is constituted by two domains: the functioning on one hand and the contextual factors on the other hand. This comprehensive-global model is able to describe the functioning (disability) from any health problem. However it remains necessary to develop new tools to better use the ICF model making it more intelligible and useful in clinical practice. For this, we proposed to use the Knowledge Discovery in Database (KDD). KDD is a non-trivial process of identification of unknown, valid and potentially-exploitable structures in database. KDD permits to transform a maximum of information in easy-exploitable knowledge. From the ICF model conjoint with KDD methods, the aim of this thesis was to characterize an expert group of LLA in terms of locomotion capacity. This group and its list of relevant indicators, based on the ICF model, were determined. They can be used as a reference to compare with others LLA improving making decision of this particular population.
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The gait initiation process in unilateral lower-limb amputees when stepping up and stepping down to a new levelTwigg, Peter C., Buckley, John, Jones, S.F., Scally, Andy J. January 2005 (has links)
No / Unilateral lower-limb amputees lead with their intact limb when stepping up and with their prosthesis when stepping down; the gait initiation process for the different stepping directions has not previously been investigated. Ten unilateral amputees (5 transfemoral and 5 transtibial) and 8 able-bodied controls performed single steps up and single steps down to a new level (73 and 219 mm). Duration, a-p and m-l centre of mass and centre of pressure peak displacements and centre of mass peak velocity of the anticipatory postural adjustment and step execution phase were evaluated for each stepping direction by analysing data collected using a Vicon 3D motion analysis system. There were significant differences (in the phase duration, peak a-p and m-l centre of pressure displacement and peak a-p and m-l centre of mass velocity at heel-off and at foot-contact) between both amputee sub-groups and controls (P<0.05), but not between amputee sub-groups. These group differences were mainly a result of amputees adopting a different gait initiation strategy for each stepping direction. Findings indicate the gait initiation process utilised by lower-limb amputees was dependent on the direction of stepping and more particularly by which limb the amputee led with; this suggests that the balance and postural control of gait initiation is not governed by a fixed motor program, and thus that becoming an amputee will require time and training to develop alternative neuromuscular control and coordination strategies. These findings should be considered when developing training/rehabilitation programs.
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Which prosthetic foot to prescribe? Biomechanical differences found during a single session comparison of different foot types hold true one year laterDe Asha, Alan R., Barnett, C.T., Struchkov, Vasily, Buckley, John January 2017 (has links)
Yes / Introduction: Clinicians typically use findings from cohort studies to objectively inform judgements regarding the potential (dis)advantages of prescribing a new prosthetic device. However, before finalising prescription a clinician will typically ask a patient to ‘try out’ a change of prosthetic device while the patient is at the clinic. Observed differences in gait when using the new device should be the result of the device’s mechanical function, but could also conceivably be due to patient related factors which can change from day-to-day and can thus make device comparisons unreliable. To determine whether a device’s mechanical function consistently has a more meaningful impact on gait than patient-related factors, the present study undertook quantitative gait analyses of a trans-tibial amputee walking using two different foot-ankle devices on two occasions over a year apart. If the observed differences present between devices, established using quantitative gait analysis, were in the same direction and of similar magnitude on each of the two occasions, this would indicate that device-related factors were more important than patient-related factors.
Methods: One adult male with a unilateral trans-tibial amputation completed repeated walking trials using two different prosthetic foot devices on two separate occasions, 14 months apart. Walking speed and sagittal plane joint kinematics and kinetics for both limbs were assessed on each occasion. Clinically meaningful differences in these biomechanical outcome variables were defined as those with an effect size difference (d) between prosthetic conditions of at least 0.4 (i.e. ‘medium’ effect size).
Results: Eight variables namely, walking speed, prosthetic ‘ankle’ peak plantar- and dorsi- flexion and peak positive power, and residual knee loading response flexion, peak stance-phase extension and flexion moments and peak negative power, displayed clinically meaningful differences (d > 0.4) between foot devices during the first session. All eight of these showed similar effect size differences during the second session despite the participant being heavier and older.
Conclusions: Findings suggest that a prosthetic device’s mechanical function consistently has a more meaningful impact on gait than patient-related factors. These findings support the current clinical practice of making decisions regarding prosthetic prescription for an individual, based on a single session evaluation of their gait using two different devices. However, to confirm this conclusion, a case series using the same approach as the present study could be undertaken.
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Clinical and Biochemical Features of Adult Diabetes Mellitus in SudanAbdelgadir, Moawia January 2006 (has links)
<p>The high prevalence of diabetes mellitus among the Sudanese population is linked to obesity, poor glycaemic control and a high rate of complications. This study investigated 1/ Leptin hormone and its correlations with different biochemical characteristics in Sudanese diabetic subjects, 2/ The impact of glycaemic control on pregnancy outcome in pregnancies with diabetes, 3/ The glycaemic response to Sudanese traditional carbohydrate foods, 4/ The influence of glucose self-monitoring on the glycaemic control among this population, 5/ The health related quality of life in Sudanese subjects with diabetes-related lower limb amputation. </p><p>Leptin was significantly lower in diabetic subjects compared with controls of same BMI in both females (P =0.0001) and males (P =0.019). In diabetic subjects, serum leptin correlated positively with the homeostatic assessment (HOMA) of both beta-cell function (P =0.018) and insulin resistance (P =.038). In controls, leptin correlated only with insulin resistance. Pregnancy complications were higher among diabetic compared with control women (P<0.0001) and varied with the type of diabetes. Infants of diabetic mothers had a higher incidence of neonatal complications than those of non-diabetic women (P<0.0001). In six Sudanese traditional carbohydrate meals over all differences in incremental AUCs were significant for both plasma glucose (P = 0.0092) and insulin (P = 0.0001). Millet porridge and wheat pancakes displayed significantly lower post-prandial glucose and insulin responses, whereas maize porridge induced a higher post-prandial glucose and insulin response. In type 2 diabetic subjects SMBG or SMUG was not related to glycaemic control. In type 1 diabetic subjects, SMBG was significantly associated with better glycaemic control, as assessed by HbA1c (P=0.02) and blood glucose at clinic visits (P=<0.0001), similar associations were found for SMUG respectively. Neither glycaemic control nor glucose self-monitoring was associated with education level. Diabetic subjects with LLA had significantly poorer HRQL compared to a reference diabetic group (P=<0.0001). Duration of diabetes and amputation had negative impact on HRQL in subjects with LLA (P=<0.0001) respectively. Diabetic subjects with LLA had decreased sense of coherence and high presence of symptoms. Improving health services at the primary level is important to reduce the complications and burden of disease in the Sudanese population.</p>
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