Previous studies in Magnetically Stabilized Fluidized Bed (MSFB) are well known for conventional two-phase, gas-solid or liquid-solid fluidization. Many researchers have investigated the fluid dynamic behavior of the MSFB, however, all of these studies are based on a uniform magnetic field that is constant throughout the bed column. Currently, there are no references in the open literature indicating either fundamental or applied research with a magnetically fluidized bed where a non-uniform magnetic field is used in a two-phase liquid-solid fluidization. In this study, the fluid dynamic behavior of a Magnetically Assisted Fluidized Bed (MAFB) in a non-uniform magnetic field is experimentally observed. In the MAFB, a magnetic force, F[sub m] , is created which acts on the ferromagnetic particles (20% ferrite) by varying the magnetic field intensity from the top to the bottom of the fluidization column. However, the field gradient is kept constant throughout the bed. Because of the differences in the magnetic field intensity at any location in the bed, the particle holdup, or inversely the bed voidage, has to change to accommodate the equilibrium of forces acting on the particles (drag force, gravitational force, buoyancy force, and magnetic force). In the laboratory experiments, performed magnetic field gradient, [see PDf for equation] Alm/m, -18,289 Alm/m, -20,543 Alm/m and -33,798 A/m/m) and fluid flow rate (U[sub 0] =0.0153 m/s, 0.0176 m/s, 0.0199 m/s and 0.0222 m/s) are varied. These experiments show that the increase in the magnetic field gradient and the magnetic field intensity results in the decrease in the height of the bed, and therefore, in the decrease of the bed voidage. The dynamic pressure drop, [delta]P[sub f][sub(d)], is also experimentally measured, then converted to a corresponding voidage. The relationship between the dynamic pressure drop and the bed voidage is given by the following equation:[see PDF for equation] The fluid dynamic behavior of the MAFB is described by the equation of motion and the equation of continuity for both liquid and solid phases. A mathematical model is developed and used to evaluate the voidage distribution in the MAFB. The resulting expression for the voidage distribution in the MAFB is given as [see PDF for equation]. Experimentally obtained bed voidage data in both, laboratory experiments (1g) and on board of the NASA KC-135 plane (0g) fit very well the above equation which does not have any adjustable parameter. / Graduation date: 2001

Inaug.-dis.--Würzburg.

Thesis (M.S.)--Oregon Graduate Center, 1972.

No description available.

The major work involved is the debugging procedure on the Varian Model V-21003 electromagnet, power supply and spectrometer and the design and construction of supporting structure to house the various pieces of apparatus which were required to complete the system.Equipment which was not immediately available was then designed and constructed, with the final step being the testing. of the entire system for its integrity.Adjustments to each component was then carried out to obtain the best signal possible, noting the various changes caused by the condition and setting of each section of the system.

This thesis comprises a computer analysis of NMR-determined interatomic distance in strontium formate dihydrate. The computer program is designed to locate the hydrogen atoms associated with the water molecules in strontium formate dihydrate. The bond length of the oxygen-hydrogen bond is assumed to be fixed. The program varies the hydrogen separation, plotting total proton interaction against the hydrogen separation distance. Using Van Vleck's second moment theory, the hydrogen-hydrogen distances were determined.. The value of the second moment of the NMR absorption curve is 24.6 gauss2, obtained from investigation by Dr. D. E. Koltenbah. The result of this thesis is that the proton separation is 1.47± .02 A. This result is found to be close enough to other studies to conclude that the program analysis is essentially sound.

Superparamagnetic iron oxide nanoparticles (SPIONs), due to their controllable sizes, relatively long in vivo half-life and limited agglomeration are ideal for biomedical applications such as magnetic labeling, hyperthermia cancer treatment, targeted drug delivery and for magnetic resonance imaging (MRI) as contrast enhancement agents. However, very limited studies exist on detecting and characterizing these SPIONs in vitro in physiologically relevant conditions. It would be of interest to localize and characterize individual SPIONs at the nanoscale in physiologically relevant conditions. MFM offers great potential for this purpose. We evaluate the applicability of Magnetic Force Microscopy (MFM) in air as well as in liquid to characterize bare and SiO2 coated SPIONs on mica .The magnetic properties of bare and SiO2 coated SPIONs are compared on the nanoscale using MFM. MFM phase- shift dependence on scan height is investigated using SPION samples that have been coated in hydrophobic polymers, polystyrene (PS) and poly (methyl methacrylate) (PMMA). The polymers are used to spin-coat SPION samples and mimic cell lipid bilayers. Nanoscale MFM images of SPIONs in a liquid environment, covered with these hydrophobic polymers are also presented for the first time. The use of 3-merceptopropyltrimethoxysilane (3-MPTS) to covalently attach SiO2 SPIONs to gold substrates for the potential purpose of MFM imaging in liquid is also briefly addressed. These results will allow us to understand the feasibility of detecting magnetic nanoparticles within cell membranes without any labeling or modifications and present MFM as a potential magnetic analogue for fluorescence microscopy. These results could be applied to cell studies and will lead to a better understanding of how SPIONs interact with cell membranes and have a valuable impact for biomedical applications of all types of magnetic nanoparticles.

Multidimensional nuclear magnetic resonance (NMR) spectroscopy has become one of the most important techniques available for studying the structure and function of biological macromolecules at atomic resolution. The conventional approach to multidimensional NMR involves the sampling of the time domain on a Cartesian grid followed by a multidimensional Fourier transform (FT). While this approach yields high quality spectra, as the number of dimensions is increased the time needed for sampling on a Cartesian grid increases exponentially, making it impractical to record 4-D spectra at high resolution and impossible to record 5-D spectra at all. This thesis describes new approaches to data collection and processing that make it possible to obtain spectra at higher resolution and/or with a higher dimensionality than was previously feasible with the conventional method. The central focus of this work has been the sampling of the time domain along radial spokes, which was recently introduced into the NMR community. If each radial spoke is processed by an FT with respect to radius, a set of projections of the higher-dimensional spectrum are obtained. Full spectra at high resolution can be generated from these projections via tomographic reconstruction. We generalized the lower-value reconstruction algorithm from the literature, and later integrated it with the backprojection algorithm in a hybrid reconstruction method. These methods permit the reconstruction of accurate 4-D and 5- D spectra at very high resolution, from only a small number of projections, as we demonstrated in the reconstruction of 4-D and 5-D sequential assignment spectra on small and large proteins. For nuclear Overhauser spectroscopy (NOESY), used to measure interproton distances in proteins, one requires quantitative reconstructions. We have successfully obtained these using filtered backprojection, which we found was equivalent to processing the radially sampled data by a polar FT. All of these methods represent significant gains in data collection efficiency over conventional approaches. The polar FT interpretation suggested that the problem could be analyzed using FT theory, to design even more efficient methods. We have developed a new approach to sampling, using concentric rings of sampling points, which represents a further improvement in efficiency and sensitivity over radial sampling. / Dissertation

Magnetic particles offer attractive features, so its development in a wide range of disciplines, including medical applications, has been very fruitful. As a result of the special physical properties of magnetic nanoparticles, many potential applications are made available in biomedicine. The most important feature of these particles is its magnetic forces, and it has been utilized in applications such as magnetic separation, drug delivery, hyperthermia and magnetic resonance imaging contrast agent. The important properties of magnetic particles for biomedical applications are nontoxicity, biocompatiblilty, injectability, and high-level accumulation in the target tissue or organ to two most important property among those mentioned above are nontoxicity and biocompatiblilty for available clinical trials. Some researchers have used polymers or polysaccharides coating on these surface of the magnetic material to improve the material's nontoxicity and biocompatiblilty. Common materials are dextran, polyethylene glycol, polyvinyl alcohol, starch and chitin and so on. We embedd Fe3O4 magnetic nanoparticles into agar hydrogels in the experiment, then made into powder by drying and grinding, using XRD, FTIR, TEM, SQUID, TGA and zeta potential identification of material properties. We examined its toxicity and the possibility for large scale production. This method can make use of simple and inexpensive way to mass-produce synthetic these biocompatible magnetic materials.

The effects of crystallographic orientation, temperature and heat treatment on superelastic response of Ni45Mn36.5Co5In13.5 single crystals were investigated. Superelastic experiments with and without various magnetic field were conducted under compression on a custom built magneto-thermo-mechanical test setup. Magnetostress, which is the difference in critical stress levels for the martensitic transformation with and without magnetic field, was determined as a function of crystallographic orientation, heat treatment and temperature parameters. Magnetostress of [111] crystals was observed to be much higher than that of [001] crystals with same heat treatment. Water quenched samples have the highest magnetostress among other samples with the same orientation that were oil quenched and furnace cooled. Crystal structure and atomic ordering of the samples were examined using Synchrotron High-Energy X-Ray Diffraction to rationalize observed differences. Magnetostress levels were also traced at various temperatures. A Quantum Design superconducting quantum interference device (SQUID) was utilized to examine the magnetic properties of the material. The difference in saturation magnetization at various temperatures was analyzed to explain the temperature effect on magnetostress. Calculations based on the energy conversion from available magnetic energy to mechanical work output were used to predict the magnetic field dependence of magnetostress, which provides a guideline in material selection for the reversible magnetic field induced martensitic phase transformation. Isothermal superelastic response and load-biased shape memory response of Co48Ni33Al29 single crystals were determined as a function of temperature and stress, respectively. The aim of the work is to provide a new direction to understand the anomaly of transformation strain and hysteresis for ferromagnetic shape memory alloys. Thermo-mechanical behavior of Co48Ni33Al29 single crystal was determined by a custom built thermo-mechanical compression setup based on an electromechanical test frame made by MTS. Transformation strain was observed to decrease with increasing applied stress in isothermal tests or increasing temperature in superelastic experiments. The variation in the lattice constant in martensite and austenite was verified to account for such a trend. It was also discovered that both thermal and stress hysteresis decreased with increasing applied stress and temperature, respectively. Multiple factors may be responsible for the phenomenon, including the increase of dislocation, the compatibility between martensite and austenite phase.