As early career researchers, we all want to be successful in securing our first big grant and publishing our research findings in the most prestigious journals. To achieve this success, we need to be able to understand why our grants proposals weren't funded in a grant cycle and why we are asked to make major revisions to the manuscript that we spent so much time on already. Even worse is when we get an outright rejection and don't understand why. A very important skill as a researcher is to be able to interpret the comments from grant and manuscript reviews objectively once we recover from the initial reaction of sadness, frustration, or even anger. This session will provide strategies to tackle the reviewers' comments that will hopefully lead to a successful resubmission.