No description available.

The focus of this retrospective, descriptive study is to describe non-anogenital and anogenital injuries documented in over 5,000 sexual assault forensic medical examination (SAFME) reports of female patients. The study findings expand understanding of injuries documented following sexual assault by exploring associations between injuries and a multitude of variables: patient demographics (age, race, gender); time between assault and examination; patient-perpetrator relationship; perpetrator actions (strangulation, hit, verbally threatened/coerced, use of restraints, grabbed/held); number of assaultive acts; multiple-perpetrators; suspected drug-facilitated assaults; patient and perpetrator use of alcohol and drugs; and physically or mentally impaired patients. The various types and locations of injuries are discussed in relationship to assault history. Implications of findings on forensic nursing practice are shared to improve patient assessment and care. In addition, methods to share findings with interdisciplinary partners, including law enforcement and criminal justice system professionals, are described to improve interdisciplinary collaboration and education.

AIM The aim of the study was to conduct a process evaluation of the implementation of the HIV/AIDS counselling and treatment program (HCT) for employees to ensure the delivery of standardised, high quality and ethical HIV counselling and testing services at a selected Regional Hospital in KwaZulu-Natal. METHOD A quantitative, non-experimental descriptive evaluative design was used to conduct the study. The study consisted of a two (2) questionnaire survey of a sample of 140 participants; One for the staff working in the HCT clinic (n=8) to evaluate the implementation of the HCT activities and the other for the staff that are employed at the selected public hospital (n=132) to evaluate their knowledge, attitudes and practise towards the HCT program. A checklist of the venue was also completed to evaluate the resources available at the HCT clinic. Informed consent was obtained from each participant. SPSS version 19 was used for data analysis. RESULTS The study revealed that the implementation practises of the HCT program were not according to the National Policy for HIV Counselling and Testing Guidelines (Department of Health, 2009) with regards to the availability of resources at the HCT clinic such as HIV test kits, chairs, gloves and sharps containers were available. Privacy was maintained while resources including condoms; directions such as posters to the clinic; pamphlets and reading material were unavailable. Nurse’s knowledge and attitude was neutral. There were no correlations between nurses that attended a HIV course and those that did not. The distribution of knowledge was the same across all categories of experience and level of education. The majority of nurses had an HIV test voluntarily and found out the results. The finding of the study does not indicate whether or not the HIV test was done at the staff HCT clinic or elsewhere. A small minority reported that they tested for employer and insurance purposes. A significant proportion of participants did not test because they were afraid that a person they know may test them and tell others and also because they did not think that the medical and nursing staff kept their testing information confidential. CONCLUSIONS AND RECOMMENDATIONS For the HCT program to be successfully implemented, resources and supplies must be available at the HCT clinic should an employee wish to use its services. It is recommended that funds be made available and budgeted for to increase the supplies of HIV test kits; provide condoms, books, pamphlets and reading material at the clinic. The researcher also recommends courses be offered to nurses that are interested; include HIV/AIDS courses in the curriculum of nurses attending the college; provide in-service education/training for employees regarding the HCT program, its resources and activities; provide anti-retro viral treatment (ART) to employees at the HCT clinic in order to decrease untimely AIDS deaths. / Thesis (M.N.)-Unversity of KwaZulu-Natal.

This thesis examines the legal protection of public employees who are HIV-infected or have AIDS in Canada and the United States. Emphasis is placed on the dealing with mandatory HIV-testing schemes in each country. To this end, the first section presents medical facts about the disease itself, the transmission risks, and testing methods as ethical considerations about HIV-testing schemes. The second section addresses the protection standards guaranteed by the Constitution of the United States and compares them to the standards set out by the Canadian Charter of Rights and Freedoms . Finally, the third section compares protection offered under the Rehabilitation Act of 1973, the Americans with Disabilities Act, and the Canadian Human Rights Act.

No description available.

This thesis evaluates the art involved in the process of constructing borders. I review the governmental processes involved with Canadian border policies as they facilitate the welcomed and the rejected. I ask: how do citizenship and immigration policies operate to maintain and reproduce borders, separating Canadian citizens inside the state from ‘foreigners’ outside. This thesis considers borders not only as repressive instruments for exclusion but also in a productive sense as they create citizens, national identities and populations. The thesis focuses on one central assemblage of border technologies: immigrant medical examinations. By reviewing citizenship and immigration policies, laws and practices since confederation, as well as contemporary legislation, policies and interview data, this thesis argues that these examinations are founded on principles of exclusion. While current policy directions suggest using these medical examinations for inclusive practices, I argue that such inclusive practices still reify the exclusive expectations of the state for citizens to be healthy and productive in the present and in the future.

This thesis evaluates the art involved in the process of constructing borders. I review the governmental processes involved with Canadian border policies as they facilitate the welcomed and the rejected. I ask: how do citizenship and immigration policies operate to maintain and reproduce borders, separating Canadian citizens inside the state from ‘foreigners’ outside. This thesis considers borders not only as repressive instruments for exclusion but also in a productive sense as they create citizens, national identities and populations. The thesis focuses on one central assemblage of border technologies: immigrant medical examinations. By reviewing citizenship and immigration policies, laws and practices since confederation, as well as contemporary legislation, policies and interview data, this thesis argues that these examinations are founded on principles of exclusion. While current policy directions suggest using these medical examinations for inclusive practices, I argue that such inclusive practices still reify the exclusive expectations of the state for citizens to be healthy and productive in the present and in the future.

South Africa’s Constitution and the Employment Equity Act have a major impact on the performance of medical examinations within the employment relationship. Health and safety statutes list a number of occupational medical examinations, which an employer must perform. Other legislation permits the execution of medical examinations. After listing the different statutory references to occupational medical examinations, this treatise examines under which conditions medical testing is required or permissible. The fairness of employment discrimination based on medical facts, employment conditions, social policy, distribution of employee benefits and inherent job requirement is analysed through a study of the legal texts, experts’ opinions and case studies. The particularities of the ethical and legal duties of the medical professional, performing the occupational medical examination, are also examined. Finally, a comprehensive analysis of the different forms of occupational medical examinations is compiled by combining legal and policy-related job requirements and is attached as an annexure. This is the practical result of the research in this treatise combined with the personal experience of the author.

This study was designed to answer the following research questions: "Are those at risk for coronary heart disease being screened for high blood cholesterol?" and "Are those with high blood cholesterol being treated according to the national guidelines?" The importance of early detection and treatment of high blood cholesterol is vital for preventive health care. A chart review of patient records was conducted to determine the behavior of the family practice residents. From the analysis of data it was determined that the residents screened their patients 83.0% of the time and when compared with national guidelines, treated those patients identified with high blood cholesterol 52.8% of the time. Third year residents screened their patients more (88.7%) for blood cholesterol than first (82.1%) or second (74.7%) year residents. Male residents screened a higher percent of their patients (84.8%) than female residents (75.0%). / Department of Physiology and Health Science

Submitted by Marco Antonio Oliveira da Silva (maosilva@ipen.br) on 2016-12-22T11:54:03Z No. of bitstreams: 0 / Made available in DSpace on 2016-12-22T11:54:03Z (GMT). No. of bitstreams: 0 / A endostatina (ES) é uma proteína inibidora da angiogênese, com ação específica sobre células endoteliais em proliferação, utilizada para tratamento de tumores sólidos. No entanto, o elevado efeito antitumoral da ES observado em animais não é reproduzido em humanos. Com o intuito de potencializar a eficácia terapêutica da ES, produzimos duas proteínas híbridas com dois domínios funcionais. O primeiro domínio é a ES, que apresenta especificidade por células endoteliais ativadas, dirigindo estas proteínas de fusão às células endoteliais em proliferação, promovendo sua internalização e seu efeito inibitório. Como segundo domínio funcional utilizamos os domínios BH3 próapoptóticos de duas proteínas BH3-only com o objetivo de promover a liberação de citocromo C e desencadear o processo de apoptose, aumentando a ação antiangiogênica da ES. Neste trabalho, foram desenhadas duas proteínas de fusão que contêm o domínio BH3 das potentes proteínas pró apoptóticas PUMA e BIM (ES-PUMA e ES-BIM), que deveriam apresentar efeito antiangiogênico potencializado em relação à ES selvagem. A inserção dos fragmentos de DNA codificantes para os domínios BH3 de PUMA e BIM no vetor contendo o gene da ES (pET-ES) foram realizadas por mutagênese sítiodirigida. Estas proteínas de fusão recombinantes foram expressas como corpos de inclusão em E.coli, renaturadas utilizando processo que utiliza alta pressão e purificadas em resina de afinidade por heparina. O tratamento de células endoteliais com as proteínas ES-PUMA e ES-BIM não levou à queda de viabilidade em ensaio de MTS ou de apoptose avaliado por citometria de fluxo, em comparação com os resultados obtidos pelo tratamento com ES. / Dissertação (Mestrado em Tecnologia Nuclear) / IPEN/D / Instituto de Pesquisas Energéticas e Nucleares - IPEN-CNEN/SP