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Origami-inspired and deployable technology has become increasingly common in a variety of applications including satellite and antenna designs for space applications. The drive to utilize ultra-thin materials in the design of these deployable space structures has led to the development of membrane hinges. Membrane hinges show promise as an effective surrogate fold because of their potential advantages including requiring minimal volume and mass, allowing for small bending radii, and functioning without lubricant. Two challenges associated with membrane hinges include reliability after repeated cyclic loading and predictability of a large deployable with radially-unconstrained membrane hinges. The research presented includes the cyclic testing and a design analysis of membrane hinges in deployable systems. Additionally, demonstrations of membrane hinges in a variety of applications are included.