People with disability have been an underprivileged group in our society for long. As the problems that face them are multi-dimensional, the health care provided to them seems burden-heavy. The development of civil rights has raised the advocacy for deinstitutionalized welfare for people with disability. However, it needs to note that the roles of family major caregivers can not be omitted when discussing deinstitutionalization or the health care to people with disability. The government should look squarely at this issue in its public policies and address the family-based or female health care work. People with intellectual disability seldom get married. As a result, the female relatives or mothers play a pivotal role in providing care work. The experiences of mothers therefore will enormously assist in investigating the process of care-giving. Mothers were the main participants for the purpose of this research. Nine mothers and one father within Kaohsiung metropolitan area who perform health care to their children with disability were recruited. This study used in-depth interview in attempt to apply labeling theory to portray the stigma and unfair treatment they encountered in the society. Its particular conclusions were as follows: 1.This study consistent with some previous quantitative studies supported the finding that the problems that mothers face include metal disorders¡Bemotional depressions¡Beconomical difficulties and educational difficulties. 2.In tradition, care work is always viewed for granted as a responsibility to mothers. When health care work is needed, the responsibility undoubtedly will be distributed to them, but the decision making process does not always concern their willingness. 3.Because of the overlap between care work and paid work, mothers only seek those jobs that are un-technical, flexible and low waged. It is apparent that they still are trapped in so-called female poverty. 4.The discrimination and labeling against people with disability still exist in our society. The findings revealed that mothers take both positive and negative strategies to cope with this. The positive strategy is to strengthen their own self-confidence which is always from their participations in the society. Ignorance and avoidance however were reported as negative strategies. 5.Four mother types were constructed as a result of the enlightenment of labeling theory in the study and they are self-blamed¡Britualism¡Bself-salvation and utilitarianism from which four different types of care processes and coping strategies are developed respectively.