It is a common method to use mergers and acquisitions to grow for enterprises. Cross-border mergers and acquisitions is one of the ways to expand the oversea marker share, besides mergers and acquisitions in domestic market itself. In the past, the enterprises from developed countries took the role to buy oversee targets. The enterprises from emerging markets gradually become the protagonist for the reason of the rise of emerging markets, especially after the Global Financial Crisis and European Debt Crisis. This study refers to literature presented to look deeply into the motivations of mergers and acquisitions from different acquirers. We classified the motivations we found in the secondary data, with year 2007 to May 2012 as the scope, expecting to figure out the differences between developed-country acquirers and emerging-market acquirers. The result shows that the main motivations for developed-country acquirers are seeking for the resources needed, entering local market and increasing the size of itself. On the other hand, going into international market, reaching economy of scale and seeking for the resources needed are the main motivations for emerging-market acquirers. Furthermore, the motivation of mergers and acquisition differs from one industry to another.