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Cardiotoxic Manifestations of Mesoridazine OverdoseMarrs-Simon, Pamela A., Zell-Kanter, Michelle, Kendzierski, Donald L., Leikin, Jerrold B. 01 January 1988 (has links)
We present a case of malignant arrhythmias associated with hypocalcemia and subsequent cardiac arrest in a 20-year-old woman due to ingestion of 3.1 g mesoridazine in a suicide attempt. There were unexplained alterations in serum electrolytes preceding the cardiac arrest. The patient subsequently recovered and was transferred to a psychiatric hospital. Despite the paucity of data on the potential cardiotoxicity associated with mesoridazine overdose, this case demonstrates that malignant arrhythmias and cardiac arrest occur; consequently, these patients probably require constant ECG monitoring.
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