Soybean seed is one of the most costly inputs for soybean producers. Research was conducted in 2016 and 2017 in Mississippi to evaluate the impact of row spacing, planting date and seeding rate on soybean yield. Additional research was conducted to determine the optimal replant seeding rate, following a sub-optimal stand of soybean, to maximize soybean yield. These data suggest an early planting date, mid-April, at a seeding rate of 296,400 seeds ha-1, no matter the row spacing, resulted in the greatest soybean yield. No yield differences were observed for a replant seeding rate of 160,500 seeds ha-1 added to a 50% reduced stand when compared to the optimum stand treatment. Soybean yield was greater for the optimum stand treatment when compared to complete removal followed by full replant treatment, or 321,000 seeds ha-1.