The integration of mobile and sensor technologies, and the design and implementation of different web-enabled visualizations to support inquiry learning in different educational scenarios encompass the main research efforts carried out in this thesis. These challenges are addressed from the perspectives of mobile and web engineering, visualization and technology-enhanced learning (TEL). Thus, the main research question investigated in this thesis relates to the identification of the main features that can guide the design and implementation of web and mobile applications to support inquiry learning in different contexts. This thesis consists of a collection of four publications that describe the research efforts conducted during a period of three years in relation to the Learning Ecology through Science with Global Outcomes (LETS GO) research project. The research questions investigated and the implemented technological solutions reported in these publications are closely related to the main goals and challenges of this thesis. The design and implementation of the proposed software system was guided, deployed and refined having the following aspects in mind: (1) System Requirements and Architectural Design, (2) System Implementation and Deployment, and (3) System Assessment and Web Usability Testing. During the three years of development efforts, three software prototypes were implemented utilizing service-oriented approaches. These efforts have been tested with more than 200 users in connection to several trials that took place during this period. The user trials allowed testing the software application throughout three development iterations on authentic settings, while new requirements continuously emerged in these activities. This process made it possible to verify that user requirements were adequately addressed while satisfying their needs. The outcomes of these activities led to the design and implementation of a system architecture that relies on service-oriented approaches and open standards. The main outcomes of this thesis are presented in the form of Architectural Concepts, as they can be used to guide the design and implementation of web and mobile applications to support inquiry learning. The idea behind architectural concepts is to provide a set of tools for supporting the overall life cycle of a software development process, such as requirements, design, implementation, deployment and testing while coping with rapid changes of technological implementations. Some of the architectural concepts identified in this thesis correspond well with the kind of support that inquiry-learning activities require. They provide solid foundations in terms of possibilities to tackle the requirements for supporting inquiry learning in a flexible manner.