In this diploma thesis the seismic load on two different models is solved – the first model is a beam hall and the second model is a multistory building. The calculation of seismic load was performed according to standard ČSN EN 1998-1 (Eurocode 8) using the response spectrum analysis and the method of equivalent static forces (substi-tute load). For the combination of seismic responses in different directions are used SRSS and CQC rules. Models and calculations were solved in a student’s version of program RFEM 4.10 (Ing. Software Dlubal, s.r.o.). The comparison of mentioned methods in each models, also the comparison of combinative rules in calculation and the final evaluation of seismic responses on both of models are the subject of this thesis.