The P-delta effect, which is a second order effect, is experienced by a structure mostly when the structure is subjected to lateral forces like earthquake and wind. In addition to earthquake and wind loads, when the structure is subjected to various live load patterns other than symmetrical loading, the structure experiences side sway or lateral translation. In this thesis, P-delta effects due to symmetrical and asymmetrical live loads is studied on a three-bay, two-story steel moment frame. The main objective of this research is to investigate P-delta effects on the column which is subjected to critical load case. The effect is analyzed based on the value of the moment magnification factor, B2. Besides, the story drift due to asymmetrical loading is also investigated. For the purpose of this study, “Approximate Second-Order Analysis” specified in “Appendix 8” of AISC Steel Construction Manual (AISC 2011) is used to amplify the first order effects to account for the second-order effects in the steel moment frame. Additionally, computer software is used to calculate the first order moments and axial forces.