No description available.

The theoretical part of the thesis offers a comprehensive view on the issue of therapeutic gardens and hortitherapy. It addresses the development of therapeutic gardens in Slovakia and abroad, and defines their basic types. Therapeutic gardens for child patients represent the core of the work. Drawing from bibliographical sources, the thesis defines construction principles for these gardens. The methodology contains a detailed analysis of the current state of the model object in graphical and text form. The author presents a comprehensive proposal for the solution of an area of the model object and related rehabilitation garden for a child patient with cerebral palsy which is contained in the detailed examination of the idea. The proposal is expressed in floor plan, sections and spatial display. The proposed solution is an outcome of the use of gardens for the construction of therapeutic gardens that draws from the author's own design experience and medical advice by doctors specialising in physiotherapy and balneology. The proposal presents a space for social and physical rehabilitation of children with cerebral palsy. It utilises the potential of the area where the model object is based.

Introduction: The recurrence of the cerebral ischemic stroke after a history of TIA or ischemic stroke is 3-4% per year. One way of reducing the risk of reccurence is using antiplatelet therapy. The aim of our study was to investigate the effect of aspirin. Even though, newer antiplatelet drugs were developed, their risk/benefit profile has not been proved to be better than aspirin. Reasons for using aspirin in secondary prevention are: the longest experience, clearly proven effect in many studies and low price. On the other hand, aspirin prevents only 25% of strokes, thus there is wide space for searching for causes of failed therapy and alternative therapeutic ways. Noncompliance of aspirin use and embolic events are usually indicated as the most common causes of an ineffective therapy. The goal of our study was to find the antiplatelet therapy effectivity in patients with history of stroke treated with aspirin in daily dose of 100mg. We assured 100% compliance among these patients and as much as possible minimalized a likelihood of embolic causes of strokes. What is more, we tried to find out whether an insuffient suppression of 11-dehydrotromboxane B2 correlates with comorbidities, other used medication or laboratory parameters. Furthermore, whether by administrating an increased dose of...

Introduction: The recurrence of the cerebral ischemic stroke after a history of TIA or ischemic stroke is 3-4% per year. One way of reducing the risk of reccurence is using antiplatelet therapy. The aim of our study was to investigate the effect of aspirin. Even though, newer antiplatelet drugs were developed, their risk/benefit profile has not been proved to be better than aspirin. Reasons for using aspirin in secondary prevention are: the longest experience, clearly proven effect in many studies and low price. On the other hand, aspirin prevents only 25% of strokes, thus there is wide space for searching for causes of failed therapy and alternative therapeutic ways. Noncompliance of aspirin use and embolic events are usually indicated as the most common causes of an ineffective therapy. The goal of our study was to find the antiplatelet therapy effectivity in patients with history of stroke treated with aspirin in daily dose of 100mg. We assured 100% compliance among these patients and as much as possible minimalized a likelihood of embolic causes of strokes. What is more, we tried to find out whether an insuffient suppression of 11-dehydrotromboxane B2 correlates with comorbidities, other used medication or laboratory parameters. Furthermore, whether by administrating an increased dose of...

This thesis is focused on summarising basic knowledge about the diagnosis cerebral palsy (CP), describing the development of an indiviual with CP and on compiling a care plan from birth up to adulthood. In the theoretical part knowledge about historical aspects, risk factors, prevalence, diagnostics, classification and comorbidities of CP is summarized. In the theoretical part are also included the characteristics of each life period of an individual with CP and interventions that are usually indicated during the time, including a comparison with foreign approaches. The practical part is an overview of intervention indications in relation to age compiled from data of patients' medical documentation. These data were processed into a timeline, which is a part of this thesis.

Cognitive function disorders have an enormous impact on the life quality of a patient, his or her family and close people. It influences the patient's job, social interaction and independence. This diploma thesis focuses on the possibility of improving cognitive functions concerning multiple sclerosis with the help of facilitation physiotherapy. Twelve disordered volunteers participated a two-month physiotherapeutic programme (motor programs activating therapy), for 1 hour, twice per week. Before the beginning and after the end of the therapeutic programme an examination by a clinic test PASAT and the monitoring of functional magnetic resonance was done. The results of functional magnetic resonance were further compared with the results of group of healthy volunteers. Concerning clinic test, the results of the disordered patients have improved after the therapy. In functional magnetic resonance statistics the earlier start and change of a curve progress of brain activation was discovered, which portrays improving speed of processing information at multiple sclerosis disordered.

Recently, the literature concerned with the possibilities and limitations of working memory training has been growing rapidly. Nonetheless, there are still no clear answers about the principles of its effectiveness or transfer effect. The main questions we ask are about effectiveness of cognitive training in patients after stroke or TBI. To our knowledge this group hasn't been studied in this context yet. To do this, we compare two types of cognitive training - extensively studied N-back training (n=11) and still more popular group cognitive therapy (n=9) with a placebo control group (n=5) who recieves "training" in a simple computer game. The placebo control group then continues in N-back training. Our hypothesis is that after 3 weeks the two trainings should lead to significantly higher gains in cognitive tests scores than the placebo condition. Also, we expected N-back to be more effective than group cognitive training in domains more closely related to executive control. We tested attention, fluid intelligence, short-term and working memory. We also recorded participants well-being. Following training, there were no significant differences between N-back and group training. N-back group scored significantly higer on Trail Making Test A than control group (p=0,026). Although our study doesn't...

Title: Using Virtual Reality as a Therapeutic Modality for Children with Cerebral Palsy: a Review and Synthesis Author: Bc. Petra Smolová Grammar correction: Jan Valeška Background: Cerebral palsy is often referred to as an" umbrella term" denoting a group of non-progressive conditions involving primarily a disorder of voluntary movement and/or co-ordination. A functional impairment is more important than diagnosis itself, due to the lifelong type of the disease. Therapy in children suffering from CP is nowadays based on individual movement therapy within a whole complex of rehabilitation programmes. The first line of treatment is building up an interdisciplinary team of professionals, led by paediatrics neurologist or neurologist who is pursuing rehabilitation. Physical therapist should always choose an eclectic approach, knowing only too well the reasons why. Virtual reality as a therapeutic modality is standing besides classic methods according to various authors, as we know from schools and different courses. However, this kind of treatment is novel, its results are greatly promising based on current research. Aim: The purpose of this thesis is to outline the use of virtual reality as a method of therapy in children with cerebral palsy in the main functional conditions - motor control, upper...

Title: Acute neuroinflammatory reaction after focal cerebral ischemia Aim: The aim of this thesis is to evaluate neuroinflammatory response after focal cerebral cortical ischemia. Also, familiarizing with the method of displaying damage of blood brain barriers, neurons and the possibility of detection of microglia cells as a marker of acute neuroinflammatory processes. Methodology: This is an experimental study. We brought about cortical cerebral ischemia in rats using an application of photosensitive dye "bengal red," and a green laser. Two animals were were given the additional application of "Evans blue" in order to visualize the defects of the blood brain barrier. The animals were returned to their cage for the time needed before they were induced terminal anesthesia. This was followed by the process of brain perfusion, slicing the brain in sections 50 µm thick and then applied these sections onto slides. Sections with applied EB were immediately analyzed under the microscope. Sections to illustrate neuronal death were immunohistochemically stained via the Nissl method. Sections visualizing microglial activity were stained using CD11b antibody. Results: Following the induction of focal ischemia there occured brain tissue damage. In the vicinity of lesion there is degeneration of neurons and...

1 Abstract Title: Consequences of experimentally induced perinatal cerebral ischemic lesion. Aim: This thesis aims to present the issues and analyze current knowledge in the field of perinatal brain damage, particularly perinatal cerebral ischemic lesions as the most common brain infarction in children. Basic characteristics of the disease, syndromology, pathophysiological mechanisms and risk factors are emphasized. Following the theoretical background the thesis analyzes current trends as well as the limitations of the diagnostics and therapy. The aim is to highlight the need for early diagnosis and emphasize the potential of preventive treatment strategies. The practical part follows the theoretical background and expands the topic on the analysis of motor and behavioral consequences of experimentally induced perinatal ischemic stroke. Method: Cerebral focal ischemia was induced experimentally by photothrombotic method to seven days old rats. Rose Bengal intravenously followed by continual illumination of the senzorimotor cortex using a green laser beam for 10 minutes was induced platelet aggregation and subsequent thrombosis. Eight animals at age of two months were evaluated for 7 days via observational cages PhenoTyper. Results: The theoretical part collected and processed theoretical data on the...