In recent years, the multilateral approach to the nuclear fuel cycle has been promoted as a potential mechanism for strengthening the nuclear non-proliferation regime. The multilateral approach has the potential to gain international favour over what has become traditional practice – the indigenous development and control of nuclear facilities. This thesis explores the way in which four states have responded to the revived attention on multilateral approaches to the nuclear fuel cycle, within the framework of the norm life cycle. The varying levels of support reflect broader international opinion on this issue, as many developing states remain concerned that they may be required to forgo not only the “inalienable right” to peaceful nuclear energy, but also the prospective economic and technological benefits of indigenous development in order to participate. However, as the risk of further proliferation and nuclear terrorism comes to the fore of international agendas, facilitating multilateral control of the most sensitive aspects of peaceful nuclear energy may be the key to strengthening the non-proliferation regime in the 21st century.