My research goal was to functionally dissect the regulatory region of the gene encoding the muscle protein troponin I (TnI) in the simple chordate Ciona intestinalis. Based on evolutionary sequence conservation and computational prediction of cis-elements in the regulatory region, I designed mutants and assayed their effects in a recombinant DNA construct reporter system. I electroporated TnI DNA-linked reporter constructs into Ciona zygotes and assayed reporter activity following 12-14 hr of development. These studies showed that a conserved E-box is essential for high-level embryonic tail muscle-specific expression whereas conserved MEF-2 and overlapping CREB/TEF-1 sites were not. I carried out functional promoter identification experiments and 5' RACE studies and localized the core-promoter/transcription start-site in the Ciona TnI gene. My results point out the similarities/differences between Ciona and vertebrate Tnl gene regulation, which presumably reflect the conservation/modification of TnI gene regulatory mechanisms during chordate/vertebrate evolution.

Thesis (M.Sc.)--York University, 1999. Graduate Programme in Kinesiology and Health Science. / Typescript. Includes bibliographical references (leaves 77-79). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pMQ56210

Thesis (Ph. D.)--University of Missouri--Columbia, 1996. / "August 1996" Typescript. Vita. Includes bibliographical references (l. 138-156). Also available on the Internet.

Thesis (Ph. D.)--Lehigh University, 1999. / Includes vita. Bibliography: leaves 161-173.

Thesis (M.S.)--California Polytechnic State University, 2009. / Mode of access: Internet. Title from PDF title page; viewed on January 20, 2009. Major professor: Scott Reaves, Ph.D. "Presented to the faculty of California Polytechnic State University." "In partial fulfillment of the requirement of the degree [of] Master of Science in Agriculture with a specialization in Food Science and Nutrition." "December 2008." Includes bibliographical references (p. 81-90). Also available on microfiche.

Thesis (M.S.)--University of Missouri-Columbia, 2008. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. "December 2008" Includes bibliographical references.

Thesis (M.Sc. Materials and Process Engineering)--University of Waikato, 2006. / Title from PDF cover (viewed April 23, 2009) Includes bibliographical references (p. 100-104)

Thesis (Ph. D.)--Michigan State University. Dept. of Neuroscience, 2008. / Cindy Jordan, graduate advisor--From acknowledgments. Title from PDF t.p. (viewed Aug. 20, 2009). Includes bibliographical references (p. 139-155). Also issued in print.

Thesis (doctoral)--University of Stockholm, 1983. / Accompanied by papers on which dissertation is based. Includes bibliographical references (p. 36-41 (first group)).

Thesis (M. Orth.)--University of Hong Kong, 2005.