Animal experiments indicate that the main form of feedback for jaw-closing muscles is from periodontal mechanoreceptors (PMRs). However, due primarily to limitations on methods, this is yet to be confirmed in humans. The main aim of this thesis was to investigate the reflex contribution of PMRs to the human jaws using vertical (axial) stimulation. To this end the electromyographic and bite force responses of the jaw to a number of different mechanical stimulus conditions, delivered to both the upper central incisors and the upper right first molars, were investigated. The principal hypothesis was that PMRs are responsible for the majority of the reflex responses seen in the human jaw muscles. Furthermore this reflex response is modulated by different characteristics of the stimulus such as: rate of rise, maximum force applied, the amount of constant offset force (preload), the level of muscle contraction and also the physical characteristics of the subject's jaw including: dental health and tooth spacing. These studies have contributed towards the understanding of the neuronal wiring and the receptor systems contained in the jaw. The results indicate that PMRs around the incisors are of fundamental importance for the development of reflex patterns but little if any PMR related reflexes exist around the molar teeth. The reflexes originating from the PMRs around the incisors are modulated by different mechanical characteristics of the stimulus, thus helping to explain how the jaw muscles perform numerous and complex patterns of activation which move the jaw in many different ways and develop forces that are optimum for the task at hand. / Thesis (Ph.D.)--School of Molecular & Biomedical Science, 2004.

Thesis (doctoral)--Karolinska Institutet, Stockholm, 1985. / Extra title page with thesis statement inserted. Includes bibliographical references.

Thesis (doctoral)--Karolinska Institutet, Stockholm, 1985. / Extra title page with thesis statement inserted. Includes bibliographical references.

Thesis (doctoral)--Karolinska Institutet, Stockholm, 1990. / Extra t.p. with thesis statement and errata sheet inserted. Includes bibliographical references.