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1	The Associations Among Dietary Fatty Acids, Plasma Fatty Acids, and Clinical Markers in Postmenopausal Women with Diabetes Baker, Nancy Carol January 2009 (has links) No description available. Nutrition diabetes postmenopausal women dietary fatty acids underreporting
2	Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer Mathew, G., Mitchell, Andrew, Down, J.M., Jacobs, L.A., Hamdy, F.C., Eaton, C., Rosario, D.J., Cross, S.S., Winder, S.J. January 2013 (has links) No / Dystroglycan is frequently lost in adenocarcinoma, but the mechanisms and consequences are poorly understood. We report an analysis of beta-dystroglycan in prostate cancer in human tissue samples and in LNCaP cells in vitro. There is progressive loss of beta-dystroglycan immunoreactivity from basal and lateral surfaces of prostate epithelia which correlates significantly with increasing Gleason grade. In about half of matched bone metastases there is significant dystroglycan re-expression. In tumour tissue and in LNCaP cells there is also a tyrosine phosphorylation-dependent translocation of beta-dystroglycan to the nucleus. Analysis of gene expression data by microarray, reveals that nuclear targeting of beta-dystroglycan in LNCaP cells alters the transcription of relatively few genes, the most unregulated being the transcription factor ETV1. These data suggest that proteolysis, tyrosine phosphorylation and translocation of dystroglycan to the nucleus resulting in altered gene transcription could be important mechanisms in the progression of prostate cancer. Androgens Cell Line Cell nucleus Dystroglycans Gene expression regulation Humans Immunohistochemistry Male Myristic acid Oligonucleotide array sequence analysis Phosphorylation Phosphotyrosine Prostate Prostatic neoplasms Protein transport Transcription factors Transcription

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The Associations Among Dietary Fatty Acids, Plasma Fatty Acids, and Clinical Markers in Postmenopausal Women with Diabetes

Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer