Obtaining an enhanced lifespan for mechanical transmissions has become a challenge in diverse application sectors. Micropitting as a contact fatigue mechanism has seriously jeopardized the well-being of rolling-sliding elements present for instance in gearboxes. Additivation through copper nanoadditives has demonstrated promising results in preventing contact fatigue. There is a need to assess the influence of copper nanoadditives on micropitting and mild wear before contemplating employing them in real transmission gearboxes. Consequently, this research work aims to acquire knowledge of the tribological behavior of rolling-sliding contacts additivated with a copper nanoadditive, emphasizing the influence of two different copper nanoadditive concentrations (0.3% and 3%) on wear and micropitting as failure mechanisms. Tests were performed using a micropitting test rig. Micropitting and wear were analyzed at different slide-to-roll ratios (1%, 5%, and 30%), different load conditions (1.5 GPa and 2.5 GPa), and different temperatures (60 °C and 100 °C), for all versions of the studied lubricant. There was no change in friction behavior between the versions of the oil additivated with the copper nanoadditive and its original version. Furthermore, it was found a reduction of micropitting for the 3% version of the studied oil in some operating conditions, and a reduction of the average wear volume for this same concentration in all studied operating conditions. On the other hand, it was found that the 0.3% version of the studied oil promoted wear with an increasing slide-to-roll ratio when compared with the original version of the studied oil. A higher reduction in wear was obtained for the 0.3% version of the studied oil with an increasing temperature when compared with the 3% version. These results indicate that copper nanoadditives exhibit the potential to reduce micropitting in non-conformal rolling-sliding contacts typically found in gears and rolling-element bearings.