MPH, Faculty of Health Sciences, University of the Witwatersrand / Introduction: South African health system embraces the District Health System model. 1 District health system includes health stations or posts, other health care facilities such as private health practitioners, community based organisations. primary health care clinics and district hospitals. District hospitals provide first level of outpatient or inpatient care for patients who have been referred by their primary care providers. District hospitals usually provide 24 hour care and are integrated into district health system. The above set up is similar in Thaba Nchu Health sub district where Dr.J.S.Moroka Hospital (DJSMH) is a district hospital and therefore, a referral point for 11 clinics within Thaba Nchu sub district and 4 clinics from the neighbouring sub district. In addition, there are 5 general practitioners rooms within Thaba Nchu sub district. The DJSMH is overburdened with increasingly high caseload. Main Aim: To evaluate the referral system in the Thaba Nchu Health Sub-district, Free State Province in terms of the factors that influences its function. Methodology: This was a descriptive study undertaken at Dr.J.S.Moroka Hospital Outpatient and Casualty departments. The study included review of routinely collected hospital information on patients’ records and registers. No intervention was done for this study. Results : The referral system within the sub district is not fully functional. Most patients that are seen in the DJSMH are self referrals. The case load and work load of the two designated areas could be reduced if most of the patients could have started and be seen at the primary health care clinics. Although the registers were helpful in collecting information, the documentation on patients’ records by health workers is not consistent; it is poor and need to be improved. The records have shown that the personnel are doing little in strengthening the referral system within the district. Conclusion: This study was the first of its kind to be done in this DJSMH. Although there are good practices with regard to referral system within the Thaba Nchu subdistrict and Dr. J.S Moroka Hospital, much still has to be done to ensure that the primary health care clinics and hospitals are effectively functioning in rendering services relevant to each level of care. More patients seen in the DJSMH are self referrals that could be managed at the primary health care clinics. The interventions recommended in this study will assist in strengthening the delivery of district health care system and in particular improve the referral system within the sub district.

This thesis concerns the role that the church can play in alleviating poverty in Black rural communities in South Africa, through a case study ofthe Thaba'Nchu community in the Free State Province. The thesis argues that the policies of racial segregation of the apartheid era impacted very strongly on the Black communities in our country. Blacks were dispossessed, marginalized and suffered greatly. It is further argued that the New Dispensation after 1994 did very little to ensure that the poor in places like Thaha'Nchu enjoyed a meaningful standard of life. Poverty has continued to be a large factor in the lives of the rural Black South Africans. This situation obliges the church according to its calling to make a difference in the lives of the rural poor communities such as in Thaba'Nchu. It is argued that the Church does have a contribution to make in development. When poverty and unemployment have entrenched themselves in the community, the Church locally and ecumenically have the capacity and the potential to wage war against the scourge. To combat poverty, a clearly drawn programme of action needs to be formulated. This research proposes a two-pronged strategy where first, hunger gets addressed and second, sustainable income generating projects are initiated to empower the poor. / Thesis (M.Th.)-University of Natal, Pietermaritzburg, 2002.

Thesis (M. Tech. (Biomedical Technology)) -- Central University of Technology, Free State, 2014. / Traditional medicine has been known by mankind since ancient times as a healthcare system. All cultures have used herbs throughout history and it was an integral part of the development of modern civilization. Primitive man observed and appreciated the great diversity of plants available to him. Plants provided food, clothes, shelter and medicine and still play a vital role in rural villages of South Africa. The medicinal uses of plants and animals have been developed through trial and error. Herbal plants produce and contain a wide variety of chemical substances that act upon the body’s immune system. The medicinal properties of Ipomoea oblongata (E.Mey.ex Choisy) in this study was to determine the phytochemical content, antioxidant, anti-cancer and anti-diabetic properties of I. oblongata (Mothokho), a medicinal plant used by traditional medical practitioners of Thaba-Nchu in the Free State. The study was carried out in order to validate the ethnomedicinal claims made by the traditional medical practitioners and to evaluate the plant’s potential as a novel therapeutic agent. Twelve traditional medical practitioners of the Kopanang Dingaka Association were interviewed on the knowledge and use of I. oblongata (Mothokho). The phytochemical constituents of the plant were determined using standard screening methods. Testing for antioxidant properties (free radical scavenging activity) was carried out by means of the 2, 2- diphenylpicrylhydrazyl (DPPH) assays. The Sulforhodamine B assay was used to screen for anti-cancer activity in breast (MCF7), colon (HCT116) and prostate (PC3) cancer cell lines. Glucose uptake in C2C12 muscle cells was used to evaluate the anti- iii diabetic potential of I. oblongata. Methanol extract was fractionated using Ultra-Pure Liquid Chromatography (UPLC) to identify active compounds. The traditional medical practitioners cited the plant roots as the main ingredient in the treatment of respiratory infections, sexually transmitted infections, postnatal womb treatments, inflammation, arthritis, wounds and cancer. The methanol extract of I. oblongata showed remarkable (99.03%, 98.39, 71.31%) antioxidant potential in all triplicates tested which explains its use in oxidative stress-related diseases such as arthritis and cancer. Phytochemical tests showed the presence of carbohydrates, glycosides, steroids, terpenoids, alkaloids, flavonoids and tannins. However, the extracts were inactive against the cancer cell lines used. Glucose uptake by the C2C12 muscle cells was increased by over 150% and was comparable to that of insulin and metformin, suggesting good anti-diabetic activity. Predicted compounds found were dihydroquercetin pentaacetate, actinorhodin and actinorhodine, using Chemspider analysis. These are possible compounds that could be found in the Ipomoea oblongata extracts when using nuclear magnetic resonance (NMR) to determine the structure and names of the active compounds. Ethnobotanical uses of Ipomoea oblongata were found to have a link with other ethnobotanical studies to capture the indigenous knowledge, culture and therapeutic uses. The phytochemical results of Ipomoea oblongata can contribute to the knowledge of new drug development as indicated by literature (Harbone; 1973, Soforowa, 1993; De et al., 2010) that plants contain phytochemical contents and phenolic compounds that are valuable as medicinal properties. Methanolic extract of Ipomoea oblongata presented high levels of antioxidant activity respectively, which can become a potential iv antimicrobial agent and remedy oxidative stress related diseases. The anticancer properties were inactive and the cytotoxicity levels were found to below in I. oblongata. Low levels of cytotoxicity allow medicinal plants to be consumed by humans with fewer side effects however doses must be standardized. High levels of glucose uptake in muscle cells were indicated from the aqueous extract of Ipomoea oblongata, therefore showing great potential as an antidiabetic agent. Many medicinal plants have been validated as antidiabetic therapeutic agents in South Africa and the world. New treatment of cancer, diabetes, bacterial and viral infections is required from natural products that are cost effective with minimal side effects that can be used in health care systems. There is a correlation between the medicinal properties found in I. oblongata and the ethnomedicinal uses cited by the traditional medical practitioners. The plant I. oblongata has six ethno-pharmaceutical uses. I. oblongata is a good source of anti-diabetic and antioxidant agents that can be developed further. However the plant is not a good source of anticancer properties. Future research will be into the isolation and identification of the active compounds.

This dissertation examines the dynamics of the oral communication which takes place in the Easter Vigil at St. Augustine's Anglican Church, Thaba 'Nchu. The study uses an analytical framework drawn from Orality Theory and Speech Act Theory, to analyse oral communication in the preaching and singing of the Vigil. Through an approach of Participant Observation, details were obtained of the Easter Vigils of 1994, 1995 and 1996. The historical and cultural background of this All-Night Vigil is traced in European Church History and African Traditional Religion. The roles of the Mothers' Union, the St. Agnes Guild and the Guild of Bernard Mizeki are also highlighted. / Missiology / M.Th (Missiology)

This dissertation examines the dynamics of the oral communication which takes place in the Easter Vigil at St. Augustine's Anglican Church, Thaba 'Nchu. The study uses an analytical framework drawn from Orality Theory and Speech Act Theory, to analyse oral communication in the preaching and singing of the Vigil. Through an approach of Participant Observation, details were obtained of the Easter Vigils of 1994, 1995 and 1996. The historical and cultural background of this All-Night Vigil is traced in European Church History and African Traditional Religion. The roles of the Mothers' Union, the St. Agnes Guild and the Guild of Bernard Mizeki are also highlighted. / Christian Spirituality, Church History and Missiology / M.Th (Missiology)