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Intravenous Self-Administration of Morphine by Naive MiceCriswell, Hugh E., Ridings, Annette 01 January 1983 (has links)
A simple method for IV self-administration of drugs by mice is described. When morphine (0.5 mg/kg) was made contingent on a nosepoke response, naive mice increased their rate of nosepoking when compared either with animals receiving contingent saline vehicle injectionsor yoked control animals receiving noncontingent morphine.
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