This study replicated and extended previous research I had performed that suggested that a student success course is an effective intervention to assist student-athletes in the adjustment to college. Participants in the current study included 4 groups of students, including (1) non-athletes and (2) student-athletes who were mandated and enrolled in the student success course, and (3) non-athletes and (4) student-athletes who were not mandated and did not enroll in the student success course. Overall, results from the current study suggested that the student success course was effective in helping non-athletes and student-athletes learn key cognitive strategies that are necessary for college success. In addition, results indicated that after taking the student success course, academically at-risk students earned equivalent grades, percentage of hours passed, and retention rates compared to their peers who were not classified as being academically underprepared. Finally, adjustment patterns of all groups were examined, with particular emphasis on the decrease in adjustment over the course of the semester that was demonstrated by the student-athletes. Intervention implications and future research directions are discussed, specifically in terms of how to address the unique needs of college freshmen student-athletes.