According to existing literature, there is a suggested correlation between certain vaccinations and oral cavity symptoms. Studies have shown that the Diphtheria, Tetanus, Acellular Pertusis, as well as Polio Vaccinations have an association with presented symptoms of bleeding gums, sores, ulcers, white spots in the mouth or on lips, and unpleasant breath odor. Although these symptoms may not occur simultaneously or directly after administration of the immunization, there has been supported evidence of correlation. Given the relevance of an association between vaccinations and orally manifested side effects, an investigation on the presence of such association with the widely administered flu vaccine was conducted. Data for this work was collected from a population including undergraduate students studying at the University of Central Florida. A brief voluntary online survey requesting demographic information regarding administration of the vaccine as well as any experienced side effects was used. The study was cohort in nature as it tracked subjects with known exposure to the flu shot in the past six months to understand the outcome of interest. Results from the survey were used to determine that there is no correlation between orally manifested side effects and administration of the flu vaccine.