Thesis (M. Phil.)--University of Hong Kong, 1974. / Mimeographed.

Thesis (M. S.)--Earth and Atmospheric Sciences, Georgia Institute of Technology, 2010. / Committee Chair: Ellery Ingall; Committee Member: Irina Sokolik; Committee Member: Josef Dufek. Part of the SMARTech Electronic Thesis and Dissertation Collection.

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This thesis described investigations into the synthesis and reactions of chiral monophosphines, in five chapters. Chapter 1 introduces asymmetric catalysis, Chapter 2 and 3 describe the synthesis of enantiomerically pure monophosphine via an oxide and borane route respectively. Chapter 4 describes the organometallic reactions of these monophosphines and Chapter 5 contains experimental details of the reactions. <strong>Chapter 1</strong> describes the importance of chirality and significant asymmetric processes. The literature methods of producing homochiral monophosphines are detailed. <strong>Chapter 2</strong> describes the synthesis of enantiomerically enriched monophosphine oxides. Diastereomerically pure (2R, 4S, 5R)-2-chloro-5-phenyl-3,4-dimethyl-1,3,2-oxazaphospholidine was prepared from PCl₃ and (-)-ephedrine. This compound was reacted with 2-adamantyl magnesium bromide to afford (2R, 4S, 5R) and (2S, 4S, 5R)-3,4-dimethyl-2-2-adamantyl-5-phenyl-1,3,2-oxazaphospholidin-2-oxide after oxidation with ^tBuOOH. An X-ray crystal structure was obtained of the R_P diastereoisomer and a detailed NMR study carried out on the S_P diastereoisomer. The R_P diastereoisomer was reacted with 2-methoxyphenylmagnesium bromide to give R_P-N-methyl-N-(1S,2S)-(1-methyl-2-hydroxy-2-phenyl)-ethyl-P-(2-methoxyphenyl)-P-(2-adamantyl)phosphinamide in 68% yield and 95% d.e. The ephedrinyl residue was replaced by O-methyl under acid catalysis with inversion of configuration and with >85% e.e. Displacement of the methoxy group using phenyl lithium occurred with inversion of configuration to give the corresponding phosphine oxide in 65% e.e., which could be reduced under forcing conditions using polymethylhydrosiloxane in the presence of Ti(OⁱPr)₄. <strong>Chapter 3</strong> describes the synthesis of enantiomerically enriched monophosphines via phosphine borane complexes. Diastereomerically pure (2R, 4S, 5R)-2,5-diphenyl-3,4-dimethyl-1,3,2-oxazaphospholidine borane was prepared directly from PhPCl₂ and (-)-ephedrine, followed by oxidation with BH₃.Me₂S. This compound reacted regiospecifically with ortho-anisyl lithium to afford the product formed by P-O cleavage with >96% d.e. and with retention of configuration at phosphorus. The ephedrinyl residue was replaced by O-methyl under acid conditions with inversion of configuration and with >98% e.e. Ferrocenyl, 1-adamantyl and tert-butyl lithium reagents displaced the methoxy group with inversion of configuration and with >92% e.e., as determined by ¹H NMR methods. The phosphine borane complexes were then reduced quantitatively with Et₂NH with retention of configuration and with >98% e.e. <strong>Chapter 4</strong> describes the synthesis of indium and rhodium complexes of (S)-t-butyl-(2-methoxyphenyl)-phenyl phosphine and (S)-ferrocenyl-(2-methoxyphenyl)-phenyl phosphine. The iridium complexes are shown to reduce a range of prochiral olefins, including Z-methyl-2-acetylamino-3-phenylpropenoate (MAC) in up to 19% e.e. The di-(R,R)-(ferrocenyl-(2-methoxyphenyl)-phenyl phosphine) rhodium complex is more selective, reducing MAC in 54% e.e., while the rhodium complex of (S)-t-butyl-(2-methoxyphenyl)-phenyl phosphine reduces MAC in 24% e.e.

Copies of author's previously published articles inserted. / Includes bibliographical references (leaves 193-215) / xiv, 216 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Studies the structure and reactivity of organic, organosilicon and organophosphorus anions in the gas phase. Theoretical ab initio calculations and collisional activation in a reverse geometry mass spectrometer revealed structural information and reactivity was probed using the flowing afterglow reactor. / Thesis (Ph.D.)--University of Adelaide, Dept. of Organic Chemistry, 1991

Thesis (Ph. D.)--University of Nevada, Reno, 2006. / "May, 2006." Includes bibliographical references. Online version available on the World Wide Web.

Thesis (M.Sc. (Forensic Science))--Mahidol University, 1979.

Thesis (Ph. D.)--University of Washington, 1999. / Vita. Includes bibliographical references (leaves 83-102).

Thesis (Ph.D.) in Chemistry--University of Maine, 2003. / Includes vita. Includes bibliographical references (leaves 138-149 ).