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Clinical Features and Pharmacologic Treatment of Paget's DiseaseHamdy, Ronald C. 01 June 1995 (has links)
Paget's disease of the bone is characterized by a focal increase in the rate of bone turnover, which goes through phases of activity and quiescence. Most patients are asymptomatic. The two cardinal features are pain and deformities, and many complications may arise. Diphosphonates and calcitonin are the main therapeutic modalities.
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