Spelling suggestions: "subject:"patyp ATPas"" "subject:"ptyp ATPas""
1 |
Monte Carlo Simulations of Oligomerized Na+,K+-ATPase / Monte Carlo simulering av oligomeriserat Na+,K+-ATPasJönsson, Jakob January 2022 (has links)
Na+,K+-ATPase (NKA) is a membrane protein which assists in maintaining the electrochemical potential across the cell membrane. It has been suggested that the oligomerization of NKA may play a role in intracellular regulation of NKA activity. Monte Carlo simulations of NKA on a picket-fence membrane model were performed to examine if clustering has an effect on NKA efficiency. The results show that for a simple model of NKA interaction, oligomerization may drastically reduce the efficiency as measured in ATP turnover rate. Introducing a rate limit shows a clear separation between monomers and higher levels of oligomerization.
|
Page generated in 0.2755 seconds