The bending strength of a commercial 0.82-inch-thick three-layered particleboard was investigated in terms of its bending moment resistance capacity. Experimental results indicated that the bending moment resistance capacity of the particleboard was governed by the tensile and compressive strengths of each of four-layered materials composing of the particleboard. A proposed mechanical model for prediction of the bending moment resistance capacity of the particleboard based on the tensile and compressive strengths of each of three-layered materials was validated experimentally. The developed mechanical model can be used to explain four different variations in terms of different combinations of layer strength properties commonly occurred in real manufacturing environment due to process variations. The optimal combination in terms of each layer tensile and compressive strength property can be obtained.