Tall ironweed (Vernonia altissima) and Canada thistle (Cirsium arvense) control in cool season grass pastures was evaluated in 2007 and 2008. Tall ironweed was evaluated in Fayette and Boone Counties, KY and Canada thistle was evaluated at Spindletop Research Farm. Herbicides applied selectively with a rope-wick were compared to a broadcast foliar spray. Treatments were a broadcast treatment, of aminopyralid + 2, 4-D and six rope-wick treatments: aminopyralid at three concentrations, glyphosate, triclopyr and clopyralid at one concentration each. The Boone County location had five broadcast foliar treatments: aminopyralid at three rates, triclopyr + fluroxpyr, and 2,4-D + triclopyr. The Canada thistle study consisted of the same six rope-wick treatments as the Fayette County tall ironweed study. A broadcast treatment of aminopyralid at 70 g a.e./ha was included in 2008. Studies were evaluated 1, 2, 3, 4, 8 and 52 weeks after treatment. Aminopyralid plus 2,4-D provided 86% control of tall ironweed 52 WAT. Aminopyralid at 20% v/v controlled 65% of tall ironweed. Canada thistle control 52 WAT ranged from 0 to 25% control for the six ropewick treatments.