Doctor of Philosophy(PhD) / Research indicates that eating disorders and anxiety disorders frequently co-occur. The prevalence of anxiety disorders amongst anorexia nervosa and bulimia nervosa samples has been reported in a number of investigations. Despite the significant number of research papers investigating the comorbidity between eating disorders and anxiety disorders, many are plagued by methodological problems, limiting the usefulness of findings. Furthermore, there is a significant lack of research examining the prevalence of eating disorders among anxiety patients, and as a result, the frequency of eating disorder pathology among patients presenting to specialty anxiety clinics is unclear. The current research investigated the prevalence of comorbid eating and anxiety disorders amongst 152 women presenting for either eating disorder treatment or anxiety disorder treatment. The prevalence of anxiety disorders was determined from a sample of 100 women presenting for inpatient and outpatient eating disorder treatment. The prevalence of eating disorders was determined from a sample of 52 women presenting for outpatient treatment of an anxiety disorder. The current study found that 65% of women with eating disorders also met criteria for at least one comorbid anxiety disorder. Furthermore, 69% reported the onset of the anxiety disorder to precede the onset of the eating disorder. Of the anxiety disorders diagnosed, Social Phobia was most frequently diagnosed (42%) followed by PTSD (26%), GAD (23%), OCD (5%), Panic/Ag (3%) and Specific Phobia (2%). We also found that 13.5% of women presenting for anxiety treatment also met criteria for a comorbid eating disorder. The results of this study suggest that the prevalence of eating and anxiety disorder comorbidity is high. It is hoped that the present research will have significant etiological and therapeutic implications and further the understanding of the development and maintenance of eating disorder pathology.

Photocopy (Vol. 1) / 2v. : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Pathology, 1981

We conducted a retrospective review of discordant pathology for lymphoma patients treated at the Princess Margaret Hospital between 2000 and 2003. We identified 2818 lymphoma patients of which 1567 (38%) met inclusion criteria with 167 discordant cases (discordance rate 15.7%). Six reviewers blinded to clinical management rated potential for harm on a minimal to severe scoring. The majority (67.6%) received a rating of moderate to severe. Review of actual clinical management revealed unnecessary surgical procedures, incorrect chemotherapy and under or over treatment of patients. For discordant cases, 8.4% were identified as having severe actual harm. This means that 1/6 patients diagnosed with lymphoma may have a change in diagnosis after pathologic review, 1/9 will have discordance with the potential to cause moderate to severe consequences, and 1/75 will experience significant clinical harm. We conclude that pathologic discordance in lymphoma is common and can lead to patient harm.

We conducted a retrospective review of discordant pathology for lymphoma patients treated at the Princess Margaret Hospital between 2000 and 2003. We identified 2818 lymphoma patients of which 1567 (38%) met inclusion criteria with 167 discordant cases (discordance rate 15.7%). Six reviewers blinded to clinical management rated potential for harm on a minimal to severe scoring. The majority (67.6%) received a rating of moderate to severe. Review of actual clinical management revealed unnecessary surgical procedures, incorrect chemotherapy and under or over treatment of patients. For discordant cases, 8.4% were identified as having severe actual harm. This means that 1/6 patients diagnosed with lymphoma may have a change in diagnosis after pathologic review, 1/9 will have discordance with the potential to cause moderate to severe consequences, and 1/75 will experience significant clinical harm. We conclude that pathologic discordance in lymphoma is common and can lead to patient harm.

published_or_final_version / Psychiatry / Master / Master of Philosophy

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This study examined the utility of the Dean-Woodcock Emotional Status Examination (D-WESE). As part of the Dean-Woodcock Neuropsvchology Battery, the D-WESE is a 50-item measure of emotional functioning. Its ability to predict pathology as compared to the MMPI Clinical Scales was investigated. The D-WESE gains information about a wide range of symptoms within a short period of time.An existing data set was utilized in this study. It included 207 patients referred for psychological and neuropsychological evaluation from a large outpatient Midwestern neurology practice. The age ranged between 13 and 96 years (M = 56.53).The results of an exploratory factor analysis with oblique rotation revealed an 11factor solution consisting of eigenvalues greater than 1.00. The D-WESE factors were significantly correlated with the MMPI Clinical Scales and a poor to good percent (1670%) of the variance could be accounted for through Stepwise Multiple Regressions. The results were discussed in terms of their relationship with established MMPI codetypes. Overall, the D-WESE was found to have a moderate degree of overlap and predictive validity as compared to the MMPI. / Department of Educational Psychology