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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Physical chemical studies on electron transfer components and phospholipid-cytochrome c complexes

Yang, Pauline Yun-Wo Chen, January 1963 (has links)
Thesis (Ph. D.)--University of Wisconsin--Madison, 1963. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 106-112).
2

Studies on the hormonal regulation of hepatic phospholipid metabolism

Sommerman, Eric Frank January 1982 (has links)
Investigations were carried out on the role of glucagon and calcium in the regulation of hepatic phospholipid biosynthesis. It was found that glucagon inhibits de novo phosphatidylcholine biosynthesis in cultured rat hepatocytes. This inhibition was associated with an inhibition of CTP:phosphochocline cytidylyltransferase activity, which is the regulatory enzyme for phosphatidylcholine biosynthesis. Calcium was shown to inhibit the uptake of choline in hepatocytes by decreasing the Vmax of the saturatable uptake system. It also slightly inhibited the rate of phosphatidylcholine biosynthesis by the de novo pathway, but not by the N-methylation of phosphatidylethanolamine. However, these experiments were difficult to interpret due to the use of ionophore A23187 to vary cytosolic calcium concentrations. This ionophore has many other effects on hepatocytes which could indirectly alter the synthesis of phosphatidylcholine. In vitro studies were carried out to determine the effect of calmodulin on CTP:phosphocholine cytidylyltransferase activity. Although calmodulin did not effect the activity under the conditions of the assay, an impurity of some calmodulin preparations was found which inhibited the cytidylyltransferase in a calcium independent fashion. The inhibitor had some peptide like properties. The effect of calcium on the incorporation of[3- ³H] serine into phospholipids was also investigated. Calcium was found to increase the amount of label recovered in phospholipid. It was also found that,the label was rapidly transfered from phosphatidyserine to phosphatidylethanolamine. On the basis of these results, a model is presented for the relationships between calcium and phosphatidylserine metabolism. / Medicine, Faculty of / Biochemistry and Molecular Biology, Department of / Graduate
3

Synthetic phospholipid-peptide conjugates : biomolecular building blocks for receptor activating structures

Winger, Theodore Medard 12 1900 (has links)
No description available.
4

Charge transfer through layers of self-assembling molecules : double-layer studies

Kaufmann, Stefan January 1993 (has links)
No description available.
5

Novel vesicles from surfactant mixtures for use in topical drug delivery

Assaf, Shereen Mashhour T. January 1992 (has links)
No description available.
6

Experimental and theoretical investigations of charged phospholipid bilayers

Graham, Ian Stanley. January 1987 (has links)
Lipid systems containing charged species are examined by both experiment and theory. Experimental studies of the mixing of phosphatidylcholine or phosphatidylethanolamine with phosphatidic acid show that calcium induces fast ($ leq$1s) phase separation of these otherwise miscible systems, and that this can occur in an isolated bilayer. Ionogenic behaviour is theoretically investigated using a new electrolyte model which explicitly includes both the solvent and particle sizes, and a binding model which uses Guggenheim combinatorics to treat non 1-1 binding stoichiometries. This work predicts a reduced dielectric constant near charged surfaces and strong repulsive forces between closely spaced ($<$15A) surfaces. A reanalysis of data from charged monolayers experiments indicates (1) that the new electrolyte model describes double layer behaviour at high surface charge densities better than the traditional Derjaguin - Landau - Verwey - Overbeek (DLVO) theory, (2) that calcium and magnesium bind to phosphatidylserine monolayers with a 1-1 stoichiometry.
7

Characterization of phospholipid transfer protein (PLTP) in hepatocellular carcinoma

Lo, Ka-kin. January 2007 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2007. / Also available in print.
8

Origin and composition of phospholipids in chick embryo and chick embryo brain during development /

Siek, Theodore John. January 1964 (has links)
Thesis (Ph. D.)--Oregon State University, 1965. / Typescript. Includes bibliographical references (leaves 121-125). Also available on the World Wide Web.
9

Contribution à l'étude du métabolisme des phospholipides chez les crustacés

Chapelle, Serge. January 1984 (has links)
Thesis--Université de Liège. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (p. 316-334).
10

Contribution à l'étude du métabolisme des phospholipides chez les crustacés

Chapelle, Serge. January 1984 (has links)
Thesis--Université de Liège. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (p. 316-334).

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