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Studies of molecular dynamicsSummerfield, Dean January 1995 (has links)
No description available.
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Development of photodissociation methods for biomolecule analysis in a quadupole ion trap mass spectrometerWilson, Jeffrey John, 1979- 07 September 2012 (has links)
Photodissociation methods have been implemented and compared to collision-induced dissociation (CID) in a quadrupole ion trap mass spectrometer for the structural analysis of peptides, proteins, oligosaccharides, DNA and DNA/drug complexes. Infrared multiphoton dissociation (IRMPD) was applied to N-terminally sulfonated peptides which offers efficient photo-fragmentation and detection of important low m/z fragments in comparison to CID. Upon IRMPD of these modified peptides a simplified MS/MS spectrum comprised of only characteristic y ions allows for better identification through de novo software analysis. Oligonucleotides can undergo highly efficient IRMPD due to the phosphate moiety located on along their backbone structure which yields excellent photon absorption at [lambda] = 10.6 [mu]m. IRMPD fragmentation pathways of DNA and DNA/drug complexes were shown to be comparable to CID, yielding cleavage at the [w / (a - B )] bond, except IRMPD allows for significantly improved MS/MS sensitivity through the secondary dissociation of uninformative duplex base losses which can further dissociate into useful fragment ions for sequencing. Ultraviolet photodissociation (UVPD) has been applied to chromophorederivatized peptides and oligosaccharides which retains the advantages associated with IRMPD, but also has additional benefits due to the greater energy per photon at 355 nm (3.5 eV / photon) in comparison to 10.6 [mu]m (0.12 eV / photon). Primarily, UVPD provides highly efficient secondary dissociation of chromophore-containing fragments allowing for simplified MS/MS spectra of chromophore-derivatized peptides. This concept was also implemented for the characterization of branched fluorescently-labeled oligosaccharides which produces different fragment ions complementary to CID experiments. Secondly, UVPD provides an ion activation method which is independent of the bath gas helium pressure in the ion trap in contrast to CID or IRMPD permits for optimal trap performance without compromise. Coordination of a chromogenic 18-crown-6 molecule to the lysine side chain of a peptide facilitates UVPD at both 266 nm and 355 nm. Energy absorbed by the crown ether is transferred intermolecularly to the peptide via the strong hydrogen bonds which hold the complex together, resulting in activation and fragmentation of the peptide. CID or IRMPD of these crown ether/peptide complexes results only in their disassembly without peptide fragmentation. / text
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Investigation of the Franck-Condon region photodissociation dynamics of linear and cyclic nitroalkanes using resonance Raman spectroscopy洪美思, Hung, Mei-sze. January 1998 (has links)
published_or_final_version / Chemistry / Master / Master of Philosophy
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Negative photoion spectroscopy in the extreme ultravioletScully, Shane William James January 2002 (has links)
No description available.
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Development of photodissociation methods for biomolecule analysis in a quadupole ion trap mass spectrometerWilson, Jeffrey John, January 1900 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 2008. / Vita. Includes bibliographical references.
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Mixed quantum/classical dynamics of photodissociation of H20 and ar-H20Chen, Feng, January 2004 (has links)
Thesis (Ph. D.)--Ohio State University, 2004. / Title from first page of PDF file. Document formatted into pages; contains xvii, 105 p.; also includes graphics (some col.). Includes bibliographical references (p. 101-105).
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Investigation of the Franck-Condon region photodissociation dynamics of linear and cyclic nitroalkanes using resonance Raman spectroscopy /Hung, Mei-sze. January 1998 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1998. / Includes bibliographical references (leaves 86-88).
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H atom photofragment translational spectroscopy of small moleculesReed, Claire Louise January 1997 (has links)
No description available.
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Semiclassical initial value methods for dynamicsWalton, Andrew Richard January 1995 (has links)
No description available.
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Imaging photodissociation of ICN: Employing the Method of Fluorescense Imaging by Sliced MicroscopyChiu, Pei-lun 17 January 2007 (has links)
none
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