Nitrogen use efficiency (NUE) and nitrogen (N) management practices have been an increasing concern among corn (Zea mays L.) producers. The objective of this study was to assess the placement distance of UAN and measure total N uptake on corn grain yield as affected by irrigation. Field trials were conducted in 2011 and 2012 at the Plant Science Research Center, Mississippi State, MS. Placement distance and irrigation influenced both total N uptake and grain yield results during both years of this study. Total N uptake and corn grain yield results were derived from plant samples and harvest data. Overall results from this study indicate increasing placement distance from the center of the planted row resulted in a decrease in total N uptake and grain yield. Results also show the subsurface banded treatment resulted in a greater N uptake and grain yield.