This diploma thesis aims to set a complex view on the current process of multilateral trade agreements under the World Trade Organization and point out the direction of DOHA negotiations. The emphasis is put on the Tenth Ministerial Conference, which took place in Nairobi in December 2015. Stances and demands of the WTO member are analysed step by step. The thesis considers threats that possibly come from plurilateral, bilateral and regional agreements and evaluate a potential risk for the multilateral trading system. For this purpose, the thesis is divided into four chapters. First chapter examine theoretical introduction to WTO and particularly to Development Doha Agenda, which is important for subsequent understanding of actual issues. Second part analyses in detail the negotiations in main negotiating parts of DDA before and after a summer break. Following chapter fluently continues with analyse of the progress after summer break and points out some current questions about preparations for MC10 and expectations. Space is also given to the MC10 and its outcomes. Finally, the last chapter gives a thought to future scenarios concerning function of the WTO.