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Women's experiences of traditional chinese acupuncture treatment for threatened preterm labour a thesis submitted in partial fulfilment of the requirements for the degree of Master of Health Science, Auckland University of Technology, New Zealand, February 2005.Robinson, Anneke. January 2005 (has links) (PDF)
Thesis (MHSc--Health Science) -- Auckland University of Technology, 2005. / Also held in print (iii, 122 leaves, 30 cm.) in Akoranga Theses Collection. (T 615.892 ROB)
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Integrative research review : fetal fibronectin and cervical length as predictors of preterm laborMcDonough, Susan Benvenuto 01 January 1999 (has links)
The purpose of this integrative research review is to provide a compilation and review of literature related to fetal fibronectin and cervical length relevant to the prediction of the patient at risk for preterm labor. This paper will synthesize and summarize the accumulated state of the science in this topic between the years of 1991- 1998.
A general search using key terms was conducted, and yielded 79 prospective articles comprised of full articles, abstracts, letters, and literature reviews. Twenty-eight articles on fetal fibronectin were retained out of 49 that were found. The search for literature discussing cervical length produced 16 articles, of which 11 were found to be relevant to this project. Articles which addressed both fetal fibronectin and cervical length totaled 6, of which 5 were utilized. Seven of the total 44 articles retained were literature reviews and were used for citation and identification of additional information material to this topic.
All of the studies on fFN consistently found the high negative predictive value to provide potential benefit in terms of improving the diagnosis of true preterm labor, thus increasing the accuracy of instituting appropriate interventions. Studies which examined cervical length found that a shortened cervical length and the presence of cervical funneling, correlated with a large cervical index was also consistent with preterm labor symptomology. The presence of fFN and cervical length as combined factors in the prediction of preterm delivery found that the incidence of preterm delivery when fFN is present correlated with confirmed shortening of the cervix was higher than in women negative for fFN and who enjoy normal cervical length.
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An innovative strategy to understand and prevent premature delivery the pre-pregnancy health status of women of childbearing age /Arbour, Megan Wood, January 2008 (has links)
Thesis (Ph. D.)--Ohio State University, 2008. / Title from first page of PDF file. Includes bibliographical references (p. 182-198).
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Stretch-activated potassium channels in human myometrium and aspects of cGMP signalingTichenor, Jennifer Noel. January 2008 (has links)
Thesis (Ph. D.)--University of Nevada, Reno, 2008. / "August 2008." Includes bibliographical references. Online version available on the World Wide Web.
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WOMEN'S ADAPTIVE RESPONSES TO EARLY LABOR CONTRACTIONSSchuster, Mary Francine, 1943- January 1987 (has links)
No description available.
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Progestational agents and preterm birth : an updated review of the literature.McSpadden, Amy. Caughy, Margaret O'Brien. Schecter, Arnold. January 2008 (has links)
Source: Masters Abstracts International, Volume: 46-05, page: 2669. Adviser: Margaret Caughy. Includes bibliographical references.
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Alterations in uterine and placental sodium pump abundance may contribute to the onset of mouse labor / y Carlos J. Vance.Vance, Carlos Jacob, January 2005 (has links) (PDF)
Thesis (M.S.)--Brigham Young University. Dept. of Chemisty and Biochemistry, 2005. / Includes bibliographical references (p. 46-53).
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Molecular genetic analysis of preterm labourBruiners, Natalie 12 1900 (has links)
Thesis (MSc)--University of Stellenbosch, 2007. / ENGLISH ABSTRACT: The World Health Organisation (WHO) has defined preterm labour as the onset of labour before
37 completed weeks of gestation with an incidence ranging between 5-10%. Although patient
care has improved, the rate of preterm birth has slowly been increasing and currently impacts
significantly on maternal and fetal mortality and morbidity. The complex condition of preterm
labour involves multiple etiologies and risk factors, which complicates the search for candidate
markers and / or biomarkers.
The aim of this prospective study was to investigate potential genetic associations with preterm
labour. The study cohort consisted of consecutive first-time booking, low-risk primigravid
pregnant women from a restricted geographical region.
The study cohort comprised 421 [306 Coloured and 115 Black] pregnant women presenting at the
Paarl Hospital Obstetric clinic. Subsequently, DNA was extracted from whole blood and
investigated for a range of known polymorphisms in pro-inflammatory and anti-inflammatory
cytokines, as well as the novel LGALS13 gene, for potential variants that may impact on
pregnancy outcome. Screening techniques involve combinations of allele-specific PCR
amplification, Multiphor SSCP/HD analysis, restriction enzyme analyses and DNA sequencing.
A significant association was demonstrated between the IL-1RN*2-allele and adverse pregnancy
outcome, mainly in the preterm labour and hypertension group. The presence TNFα-308 A-allele
was associated with overall adverse pregnancy outcome and preterm labour. In addition to this, a
novel IL-1RN allele was identified in the control group.
Mutation screening and subsequent statistical methods revealed an association between a novel
LGALS13 exonic variant, 221delT, and preterm labour in Coloured women. Two previouslydocumented
intronic variants (IVS2-22A/G and IVS3+72T/A) demonstrated linkage
disequilibrium, signifying evolutionary conservation of exon three. Additionally, two novel
intronic variants, IVS2-36 G/A and IVS2-15 G/A, demonstrated no association with adverse
pregnancy outcome. In this study we identified rare novel exonic variants; two non-synonymous variants in exon three
(M44V, [N=2] and K87R, [N=1]) and a silent variant in exon four (P117P, [N=1]) - all identified
in individuals from the control cohort. Within coding exon three, an interesting variant
[“hotspot”] was identified, which represents six polymorphic bases within an 11bp stretch. No
associations were demonstrated with these variants and pregnancy outcome.
Furthermore, a previously documented 5' “‘promoter” variant, -98 A/C, was identified and
demonstrated no association with adverse pregnancy outcome. However, subdivision of lateonset
pre-eclamptic cases revealed a significant association with the A-allele and late-onset preeclampsia.
Genotype-phenotype investigation demonstrated association between the IL-10 -1082 A/G, IL-4
C/T and 221delT loci and poor pregnancy progress which manifested as (i) delivery of infants
weighing <2000g, (ii) before 37 weeks of gestation.
The findings of this study will strengthen our understanding of the pathophysiology underlying
pregnancy complications and facilitate the further development of effective treatment strategies to
reduce maternal and fetal morbidity and mortality. / AFRIKAANSE OPSOMMING: Die Wêreld Gesondheid Organisasie (WHO) klassifiseer voortydse kraam as kontraksie voor 37
volledige weke, met ‘n insidensie tussen 5-10%. Alhoewel pasiënte-sorg verbeter het, neem die
tempo van voortydse geboorte steeds toe, wat ‘n groot impak het op moederstrefte en fetale
mortaliteit en morbiditeit. Die komplekse kondisie van voortydse kraam sluit veelvoudige
oorsake en risiko faktore in, wat die navorsing van kandidaat en / of biologiese merkers
kompliseer.
Die doel van hierdie prospektiewe studie, was die potensiële navorsing van genetiese assosiasies
met voortydse kraam. Die studie kohort bevat opeenvolgende eerste bespreking van lae risiko
primigravida swanger vrouens vanaf ‘n beperkte geografiese omgewing.
Die studie kohort beslaan 421 [306 Kleurling en 115 Swart] swanger vrouens teenwoordig by die
Paarl Hospitaal Verloskunde kliniek. Vervolgens was DNS geëkstraeer van bloedmonsters en
geondersoek vir ‘n verskeidenheid van bekende polimorfismes in pro-inflammatoriese en antiinflammatoriese
sitokiene, insluitend die nuwe sifting van die LGALS13 geen potensiaal vir
variante wat ‘n impak op swangerskap uitkomste sal hê. Die siftings tegnieke toegepas, sluit in ‘n
kombinasie van alleel-spesifieke amplifikasie, Multiphor enkelstring konformasie polimorfisme /
heterodupleks analise, restriksie ensiem verterings en volgorde bepalings tegnieke.
‘n Betekenisvolle assosiasie was gedemonstreer tussen die IL-1RN*2-alleel en nadelige
swangerskap, beperk tot voortydse kraam en die hipertensie groep. Die teenwoordigheid van die
TNFα-308 A-alleel was geassosieer met algehele nadelige uitkomste en voortydse kraam.
Daarby, was ‘n nuwe IL-1RN alleel geïdentifiseer in die kontrole groep.
Mutasie sifting en opeenvolgende statistiese metodes, het ‘n assosiasie getoon tussen ‘n nuwe
LGALS13 koderende variant, 221delT, en voortydse kraam in Kleurling vrouens. Twee
voorafbeskryfde introniese variante (IVS2-22 A/G en IVS3+72 T/A), het ‘n betekenisvolle bewys
opgelewer dat daar koppelings-onewewig bestaan tussen hierdie variante, en toon evolusionêre konservasie van ekson drie. Addisioneel was twee nuwe introniese variante ontdek, IVS2-36 G/A
en IVS2-15 G/A, wat geen assosiasie getoon nie.
In hierdie studie het ons ‘n nuwe seldsame koderende variante geïdentifiseer in die kontrole
groep, waarvan twee nie-sinonieme variante was in ekson drie (M44V, N=2 en K87R, N=1) en ‘n
stil variasie in ekson vier (P117P, N=1). Geleë in die koderende area van ekson drie, was ’n
interessante variant [“hotspot’] ontdek, waarvan ses basisse in ‘n 11 basis paar area polimorfies
is. Geen assosiasie was getoon met hierdie variante en swangerskap uitkomste nie.
Verder was ‘n voorafbeskryfde 5' ‘promotor’ variant, -98 A/C, geïdentifiseer wat geen assosiasie
getoon met nadelige swangerskap uitkomste nie. Onderverdeling van laat-aanvangs preeklampsie,
het getoon dat die A-alleel ‘n betekenisvolle assosiasie getoon het met die
ontwikkeling van laat pre-eklampsie.
Genotipe-fenotipe interaksies het ’n assosiasie getoon tussen die IL-10 -1082 A/G, IL-4 C/T en
221delT lokusse en nadelige swangerskap uitkomste, wat manifesteer as (i) kraam van suigelinge
wat <2000g weeg, (ii) geboorte voor 37 weke.
Die bevindings van hierdie studie sal ons basiese kennis verbeter oor die patologie beskrywend
aan swangerskap komplikasies, asook die fasilitering en ontwikkeling van effektiewe
behandelings strategieë, om moederstrefte en fetale mortaliteit en morbiditeit te verminder.
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Metabolic study of ritodrine with high performance liquid chromatography /Borrisud, Matana January 1983 (has links)
No description available.
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A retrospective study regarding the relationship between antenal care (ANC) adequacy and preterm birthGwatikunda, Sikhangezile 01 June 2016 (has links)
The purpose of this study was to investigate the relationship between antenatal care (ANC) adequacy and preterm births. The researcher used the quantitative, descriptive, correlational, retrospective, case control design on a sample size of 40 cases and 80 controls. A checklist was used to collect data at one state hospital in Windhoek. When the Adequacy of Prenatal Care Use (APNCU) index was applied, premature birth was found to be less likely for women in the higher categories of care (OR 0.121; 95% CI 0.124–0.613) as compared to those in the lower categories. Similarly when the Content and Timing of care in Pregnancy (CTP) tool was used; women in the higher categories of care, were less likely (OR 0.114; 95% CI 0.012–1.056) to give birth prematurely as compared to those in the lower categories / Health Studies / M.A. (Health Studies)
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