The present study investigated the effects of anxiety management training on the reduction of Type A coronary-prone behavior in a college student population and utilized behavioral measures as well as self-report indices of change. Evaluations pre- and post-treatment included self-report measures of Type A behavior, empirically validated performance measures of the achievement-striving and time-urgency components of coronary-prone behavior, and a learned helplessness manipulation that has been associated with this behavior pattern. Analysis of covariance indicated that the treatment group changed in the desired direction on all self-report indices, and on most of the performance measures and helplessness scores that were used as dependent variables. Discussion centered on the implications of these data to theoretical and practical conceptualizations of coping behavior and coronary disease and cautions were expressed concerning clinical significance, maintenance, and generalization of results.

The purpose of this study was to delineate those variables which are indicative of the patient whose health may be adversely affected by sensitivity to chemicals. In stage One analysis, the files of 10 chemically sensitive and 10 non-chemically sensitive patients were used to establish criterion variables as previously defined by legal proceedings prior to the study. Chemically sensitive and non-chemically sensitive patients were compared on all variables included in the study to empirically determine those variables which demonstrated significant differences by chi square analysis.

Previous research suggests that sex differences in cardiovascular reactivity (CVR) are a function of differences in cognitive appraisal of stressors as masculine-relevant or feminine-relevant tasks. Two studies were conducted to examine the role of the appraised gender relevance of stressors as a mediator of sex differences in CVR. In the first study the CVR of male and female college students (<u>N</u> = 95) to the cold-pressor test (CPT) was compared under masculine-relevant and gender-neutral stressor instructions during an anticipation phase, a stressor phase, and a recovery phase. Men were expected to show greater CVR than women to the masculine-relevant CPT, but not to the gender-neutral CPT. Results supported this prediction for systolic blood pressure (SBP) and heart rate (HR) reactivity, but not diastolic blood pressure (DBP) reactivity. In the second study the CVR of male and female college students (<u>N</u> = 121) to the CPT was compared under masculine-relevant and female-relevant stressor instructions during an anticipation phase, a stressor phase, and a recovery phase. Men were predicted to show greater CVR than women to the masculine-relevant CPT while women were expected to show greater CVR to the feminine-relevant CPT. Results supported these predictions for SBP, but not HR reactivity. The results for DBP were mixed. Men did not show greater DBP reactivity than women to the masculinerelevant CPT, but women showed greater DBP reactivity than men to the feminine-relevant CPT. The potential influence of sex differences in cognitive appraisal of situations on CVR and coronary heart disease is discussed. / Ph. D.

Although research has linked the central nervous system with changes in immunoresponsivity, research on the possible role of the central nervous system in altering reticuloendothelial activity is lacking. This study investigated the possible relationship between hypothalamic structures and changes in responsivity of the reticuloendothelial system. Eight male albino rats received bilateral electrode implants in the ventromedial area of the hypothalamus and, following brain stimulation, reticuloendothelial activity was assessed 3, 6, 12, 24, and 96 hours after stimulation. Brain stimulation decreased phagocytic activity of the reticuloendothelial system. These findings may increase our understanding of a possible neural mechanism underlying relationships between stress and resistance to disease states.

The main aim of this dissertation is to discuss the way women negotiate the cultural meaning of hair loss, alopecia, as a result of undergoing chemotherapy, and to understand, accordingly, how cancer's cultural effects regarding women can be deeply different from those of men. Very few studies have been done about the cultural impact and resonance of alopecia. It is often regarded as "secondary" to other effects of chemotherapy. Because, in many cultures, head hair for women expresses or manifests attractiveness and power, to be bald is to be deprived of the ability to fit into society, whether in the public or private sphere. The study examines the representation of such women in the media, audience/subject responses to these representations, and interrogates women's identities and representations in terms of Laura Mulvey's theory of the male gaze. Women who have experienced chemotherapy-induced alopec ia were interviewed in this regard. Other contributive feminist, cultural and/or media studies works, such as those by Suzanna Walters, Susan Bordo, Naomi Wolf, Donna Haraway, Stuart Hall, Kimberle Crenshaw, and Judith Butler, help facilitate the analysis. From these perspectives, a historical analysis takes into consideration the symbolic dimension of hair, especially women's head hair, within Western cultural history, particularly in France and a multicultural America. In addition, a textual analysis looks at women, cancer, and hair loss as represented in popular culture characters and personalities. The study insists on the necessity for women to resist to the culture industries and deconstruct the male gaze, as well as the female gaze, which can both contribute to, and perpetuate women's objectification. / Includes bibliography. / Dissertation (Ph.D.)--Florida Atlantic University, 2015. / FAU Electronic Theses and Dissertations Collection

Orientador: Cláudia Aparecida Rainho / Banca: Roberta Guembarovisk / Banca: Celia Regina Nogueira / Resumo: A endometriose é uma doença inflamatória estrógeno-dependente que afeta de 5 a 10% das mulheres em idade reprodutiva. É caracterizada pela presença de tecido endometrial fora da cavidade uterina e está associada à dismenorreia, dor pélvica e infertilidade. Os níveis de expressão dos receptores nucleares SF1 (fator esteroidogênico 1), estrógeno e progesterona estão alterados no tecido endometriótico comparado ao endométrio normal. Estudos prévios relataram que os genes codificadores dos receptores dos hormônios esteróides ESR1 (receptor de estrógeno 1), ESR2 (receptor de estrógeno 2) e progesterona (PGR) apresentam promotores alternativos que são modulados epigeneticamente por alterações na metilação do DNA, que ocorre preferencialmente nas ilhas CpG presentes nestas regiões. Em células endometriais normais foi observada uma associação entre a presença de metilação e ausência de expressão dos genes SF1 e ESR2 (receptor de estrógeno â) enquanto a perda da metilação foi correlacionada com níveis aumentados de expressão gênica na endometriose peritoneal e ovariana. Com base nestas evidências, o presente trabalho investigou o padrão de metilação dos genes PGR (promotores A e B), ESR1 (promotores A e B) e uma região intragênica ao ESR2. O promotor B do gene PGR e a ilha CpG localizada na 5'UTR do gene ESR2 foram avaliadas em 44 amostras de endometriose profunda intestinal pela técnica de MSP (Methylation-Specific Polymerase Chain Reaction). Em sete destas, também foi possível a investigação na amostra pareada de endométrio eutópico. O padrão de metilação dos promotores A e B do gene ESR1 e o promotor A do gene PGR... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Endometriosis is an estrogen-dependent inflammatory disease which affects 5 to 10% of women of reproductive age. This disease is characterized by the presence of endometrial tissue outside the uterine cavity and is associated with dysmenorrhea, pelvic pain, and infertility. Abnormal expression levels of SF1 (steroidogenic factor 1), estrogen and progesterone nuclear receptors were detected in the endometriotic tissue compared to the normal endometrium. Previous studies have reported that genes encoding the steroid hormone receptors ESR1 (estrogen receptor 1), ESR2 (estrogen receptor 2) and progesterone (PGR) are characterized by alternative promoters epigenetically regulated by DNA methylation at CpG islands co-localized in these regions. In normal endometrial cells, it was observed an association between DNA methylation and absence of expression of the genes SF1 and ESR2 (estrogen receptor â), while loss of DNA methylation was correlated with increased expression levels of these genes in peritoneal and ovarian endometriosis. Based on these findings, this study investigated the methylation pattern of the PGR (promoters A and B), ESR1 (promoters A and B) genes and an intragenic region of the gene ESR2. The promoter B of PGR gene and the CpG island mapped at 5 'UTR of the ESR2 gene were evaluated in 44 samples of intestinal deep endometriosis by MSP (methylation-specific polymerase chain reaction). In seven cases, paired samples of eutopic endometrium from the same patients were also evaluated, the methylation patterns of the ESR1 gene (promoters A and B) and the promoter region A of the PGR gene were investigated in 37 samples of endometriosis. The MSP method is based on the DNA modification by sodium bisulfite, which converts unmethylated cytosines to uracil. Subsequently, the target region... (Complete abstract click electronic access below) / Mestre

Bibliography: leaves 476-502 / xvi, 502 leaves : ill ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, 1985

Self-monitoring, lowered arousal training (i.e., biofeedback and relaxation training) and maintenance follow-up appeared to contribute to effective treatment of hypertension. Cognitive therapy, while effective in treatment of some stress-related disorders, has not been studied as a specific treatment component for hypertension. The present study explored the use of cognitive therapy as a treatment variable to reduce blood pressure in hypertensive persons. The effectiveness of a multi-element treatment including cognitive therapy, blood-pressure biofeedback, and relaxation training was also assessed. Self-monitoring and maintenance training were included as a part of each treatment process.

The purpose of this study was to test the Lacey hypothesis of cardiac behavior patterns for possible use as a measure of attentiveness in a classroom where experimental variables were not controlled. Lacey's hypothesis predicted cardiac deceleration with instances of information-intake and cardiac acceleration with instances of information-processing. Third grade students in a self-contained classroom were telemetrically monitored for heart rate during reading group activities. Based on cardiac behavior, taking verbal instructions and reading aloud were improperly classified. Verbal instructions produced a mean acceleratory response instead of the predicted deceleration. Reading aloud produced a weak mean deceleratory response instead of the anticipated acceleration. The other events within the intake category and the processing category, respectively, adhered to the predicted directional responses despite their statistical nonsignificance. The methodology proved sensitive to events following the momentary state of information-handling by the individual. It was proposed that averaging of data led to loss of individual sensitivity to reading group events. Individual student attentiveness to different events may be yet studied via this objective technique.

This study compared biofeedback assisted cue-controlled skin temperature training with skin temperature biofeedback training in subjects attempting to raise the digital skin temperature of their dominant hand. In addition to classification according to training, the subjects were also divided into two diagnostic groups. One group was composed of subjects with cold hands and Raynaud's disease while the other group consisted of nonRaynaud's disease cold handed subjects. The treatment and diagnostic groups were compared along the dimensions of amount of posttreatment digital skin temperature change and degree of generalization of digital skin temperature control to a cold room challenge task.