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[9,10-methylene-¹⁴C] sterculic acid metabolism in the rat : urinary metabolites, liver tissue distribution, and induced [omega]-hydroxylase activityEisele, Thomas Anthony 02 June 1976 (has links)
Corn oil (CO) and Sterculic foetida oil (SFO) fed rats were
injected with [9, 10-methylene-¹⁴C]sterculic acid. Less than 1%
of the label was expired as carbon dioxide. The majority of the
label was excreted in the urine as short-chain dicarboxylic acids with
an intact cyclopropane ring. The major metabolites for both CO and
SFO fed rats were cis-3, 4-methylene adipic acid and cis-3, 4-
methylene suberic acid. Sterculic acid must undergo β- and
[Greek w]-oxidation to form these urinary metabolites, α-oxidation played
a minor role in the formation of cis- and trans-3, 4-methylene pimelic
acid. Rats on the SFO diet could metabolize sterculic acid faster
than fats on the CO diet. However, both CO and SFO fed rats
produced the same urinary metabolites.
CO fed rats incorporated more label from sterculic acid into
protein and acid soluble liver fractions than SFO fed rats. Less than
0.01% of the label from either group was found in liver lipid sterol
or glycerol fractions.
There was a tendency for SFO fed rats to metabolize n-[1-¹⁴C]
octadecane faster than CO fed rats. This suggests that sterculic
acid may induce [Greek w]-hydroxylation of n-octadecane. / Graduation date: 1977
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The effects of high temperature and sex on the size and variability of glands and organs in the laboratory ratHamidi, Mansour, 1934- January 1966 (has links)
No description available.
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Structure and function of 5'-nucleotidase of the rat brain黎錦明, Lai, Kam-ming. January 1991 (has links)
published_or_final_version / Biochemistry / Doctoral / Doctor of Philosophy
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Melatonin receptors in the rat uterusZhao, Hang, 趙航 January 2000 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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Melatonin receptors in the rat epididymisLi, Li, 李莉 January 1998 (has links)
published_or_final_version / Zoology / Doctoral / Doctor of Philosophy
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Spatial coding of gravitational input to the vestibuloolivary pathway and its refinement in developmentLi, Chuan, 李川 January 2005 (has links)
published_or_final_version / abstract / Physiology / Doctoral / Doctor of Philosophy
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LIPID ABSORPTION AND TRANSPORT IN THE SUCKLING RAT.FERNANDO, GERMAIN JITHENDRA. January 1982 (has links)
The suckling rat obtains about 70% of its energy from the catabolism of lipid, compared to only about 25% in the adult rat. In addition, lipids are in great demand for membrane synthesis in the rapidly growing tissues. Thus the suckling rat represents an important system in which to study lipid metabolism. In this dissertation research the following experiments were performed on rats during the suckling period: (1) Determination of the concentration and fatty acid composition of triacylglycerols, cholesteryl esters, phospholipids, and free fatty acids in dam's milk, and in suckling rat lymph, portal plasma, vena cava plasma and liver; (2) Determination of positional distribution of fatty acids among the three different positions in triacylglycerols of milk, lymph, plasma and liver; (3) Isolation of plasma and mesenteric lymph lipoproteins by density gradient centrifugation, and identification of the individual classes of lipoproteins by measurement of their density and by polyacrylamide gel electrophoresis; (4) Determination of the concentration of each lipoprotein by refractometry and determination of the concentration and fatty acid composition of different lipid components in each lipoprotein fraction; (5) Studies of physical properties of the lipoproteins using analytical ultracentrifugation; (6) Determination of apoprotein composition and concentration in each lipoprotein fraction. The results show that the suckling rat consumes a diet which is rich in medium chain fatty acids (35% of total milk fatty acids). Mesenteric lymph triacylglycerols carry a significant amount of these medium chain fatty acids, unlike the adult in which they would be transported as free fatty acids, unlike the adult in which they would be transported as free fatty acids via the portal vein. Medium chain fatty acids are enriched at the sn-3 position in all triacylglycerols. Lymph contains chylomicrons, very low density lipoproteins, and high density lipoproteins, but no low density lipoproteins. Plasma contains all classes of lipoproteins but at concentrations higher than found in the adult, especially low density lipoproteins which are present at levels six times that found in the adult. The plasma very low density lipoproteins have a lipid composition which resembles that of chylomicron remnants. Apoprotein, lipid composition, and electrophoresis patterns show that the plasma lipoproteins in the suckling rat are heterogeneous.
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INDUCTION OF HEPATIC ORNITHINE DECARBOXYLASE AND PLASMINOGEN ACTIVATOR AFTER SYSTEMIC ADMINISTRATION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE IN THE RAT.Buckley, Arthur R., 1951- January 1983 (has links)
No description available.
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THE ROLE OF COENZYME-A IN ACRYLAMIDE NEUROTOXICITY IN THE RAT.Miller, Mary Jo. January 1982 (has links)
No description available.
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Effects of human chorionic gonadotropin and luteinizing hormone on rat gonadal phosphofructokinase activity.January 1977 (has links)
Simon, S.C., Chiu. / Thesis (M.Ph.)--Chinese University of Hong Kong. / Bibliography: leaves 65-71.
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