We previously reported that ovulation rate, but not pregnancy rate or litter size at d 30 post-mating, was enhanced by gonadotropin treatment (P.G. 600; Intervet America Inc., Millsboro, DE) in gilts fed a progestin (Regu-mate; Intervet America Inc.) compared with gilts receiving progestin alone. We hypothesized that P.G. 600 altered the timing of ovulation, therefore mating gilts 12 and 24 h after first detection of estrus, as is common in the swine industry, may not have been the most appropriate breeding regimen. The objective of this study was to determine the effect of P.G. 600 on the timing of ovulation in gilts treated with Regu-mate. Randomly cycling, crossbred gilts (5.5 m of age, 117 kg BW, and 14.7 mm BF) were fed a diet containing Regu-mate to provide 15 mg/d for 18 d. Twenty-four h after Regu-mate withdrawal, gilts received i.m. P.G. 600 (n = 25) or saline (n = 25). Gilts were checked for estrus at 8 h intervals. After first detection of estrus, trans-rectal ultrasonography was performed at 8 h intervals to determine the time of ovulation. Gilts were killed 9 to 11 d after the onset of estrus to determine ovulation rate. All gilts displayed estrus by 7 d after treatment with P.G. 600 or saline. Compared with saline, P.G. 600 increased (P = 0.07) ovulation rate (14.8 + 1.1 vs. 17.5 + 1.0, respectively). The intervals from injection-to-estrus (98.4 + 2.7 vs. 110.9 + 2.7 h; P < 0.01) and injection-to-ovulation (128.6 + 2.8 vs. 141.9 + 3.2 h; P < 0.01) were decreased in gilts treated with P.G. 600 compared with gilts treated with saline. Estrus duration (54.4 + 2.3 vs. 53.7 + 2.5 h; P = 0.83), estrus-to-ovulation (30.2 + 2.0 vs. 31.7 + 2.2 h; P = 0.62) and time of ovulation as a percentage of duration of estrus (55.8 + 2.7 vs. 57.5 + 3.0%; P = 0.67) were similar for the P.G. 600 and saline-injected gilts, respectively. In summary, P.G. 600 advanced the onset of estrus and ovulation following termination of Regu-mate treatment and increased ovulation rate. However, treatment of gilts with P.G. 600 had no effect on the timing of ovulation relative to the onset of estrus. / Master of Science

Lethal automated weapon systems (LAWS) are developed and deployed by a growing number of state and non-state actors, although no international legally binding framework exists as of yet. As a first attempt to regulate LAWS the UN appointed a group of governmental experts (GGE) to create the guiding principles on the issue of LAWS AI. A few years later the EU appointed an expert group to create the Ethics guideline for trustworthy and the European Parliament passed a resolution on the issue of LAWS.  This thesis attempts to make the underlying norms and discourses that have shaped these guiding principles and guidelines visible. By scrutinizing the documents through the ‘What’s the problem presented to be’-approach, the discursive practices that enables the framing is illuminated. The obscured problems not spoken of in the EU and UN documents are emphasised, suggesting that both documents oversimplifies  and downplays the danger of LAWS, leaving issues such as gender repercussions, human dignity and the dangers of the sophisticated weapons system itself largely unproblematised and hidden behind their suggested dichotomised and anthropocentric solutions, which largely results in a simple “add human and stir”-kind of solution. The underlying cause of this tendency seems to stem from a general unwillingness of states to regulate as LAWS are quickly becoming a matter of have- and have nots and may potentially change warfare as we know it. A case can also be made as to AI’s ‘Hollywood-problem’ as influencing the framing of LAWS, where the dystopian terminator-like depiction in popular culture can be seen reflected in international policy papers and statements.