Orientador: Luiz Antonio Vane / Banca: Eliana Marisa Ganem / Banca: Yara Marcondes Machado Castiglia / Banca: Maria José Carvalho Carmona / Banca: Ismar Lima Cavalcanti / Resumo: Efeitos das catecolaminas sobre a reposi€çãoo vol„êmica com solu€ção fisiolˆógica. Repercussão sobre a variabilidade da frequ„ência cardŠíaca de coelhos submetidos Œ à hemorragia. Estudo por an†álise espectral. Verificar os efeitos de diferentes catecolaminas sobre a expansão volê„mica e sobre o sistema nervoso autonôƒmico em coelhos submetidos Œà hemorragia. Foram estudados 24 coelhos, submetidos Œà hemorragia (25% da volemia), distribuŠídos aleatoriamente em quatro grupos experimentais, conforme o tipo de reposi€ção vol„êmica realizada. Grupo HEMO - reposi€ção com o prˆóprio sangue com volume igual ao retirado. Grupo SF - reposição com solu€ção fisiolˆógica (SF) em volume correspondente a tr„ês vezes o volume de sangue retirado. Grupo ISP - reposi€ção com SF em volume correspondente a tr„ês vezes o volume de sangue retirado, e Isoprenalina na dose de 0,1g.kg-1.min-1, e Grupo FNL - reposi€ção com SF em volume correspondente a tr„ês vezes o volume de sangue retirado, e Fenilefrina na dose de 3,0g.kg-1.min-1. Durante o experimento, foram monitoradas as seguintes vari†áveis: hematóˆcrito (para avalia€ção da retenç、o intravascular da soluç、o cristaloide), diurese, pressção venosa central (PVC) e pressão arterial mé‹dia (PAM). Tamb‹ém foi feito o registro contŠínuo da onda da pressão arterial donde analisando-se o pico sistˆólico aferiu-se a variabilidade da frequ„ência cardŠíaca (VFC) nos perŠíodos correspondentes Œà: basal, hemorr†ágico, infusção de catecolaminas e controle póˆs-reposi€ção vol„êmica. A reposi€ção com SF associado a catecolaminas α ou β agonistas não demonstrou diferen€ças no que tange Œ reten€ção intravascular comparando-se Œreposi€ção isolada com SF. A diurese total foi maior no grupo FNL quando comparando-se... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: The effect of catecholamines over volemic reposition with saline solution and its effects on the heart rate variability on rabbits subjected to hemorrhage. Research through Spectral Analysis. To check the effects of different catecholamines on the volemic expansion and on the autonomic nervous system of rabbits subjected to hemorrhage. 24 rabbits were studied, subjected to hemorrhage (25% volemia), randomly distributed in four experimental groups, according to the type of volemic reposition done. HEMO Group: Reposition administered with the animal's own blood, in the same amount of blood taken out. Saline Solution (SS) Group: Reposition with SS, three times the amount of blood withdrawn. Isoprenaline (ISP) Group: Reposition with SS, three times the amount of blood taken out, and Isoprenaline at 0,1g.kg-1.min-1; and Phenylephrine (PHN) Group: Reposition with SS three times the amount of blood withdrawn, and Phenylephrine at 3,0g.kg-1.min- 1. During the experiment, the following variables were monitored: hematocrit (to evaluate intravascular retention of the crystalloid solution), diuresis, central venous pressure and medium blood pressure. The blood pressure curve was also checked and by examining the systolic peak, the heart rate variability was verified during these different stages: basal, hemorrhagic, catecholamine infusion and post volemic reposition control. The reposition done with SS mixed in agonist α or β catecholamine did not demonstrate differences in intravascular retention, when comparing to isolated reposition with SS. Total diuresis was bigger in the PHN Group than in the HEMO Group. The Central Venous Pressure was significantly higher in the group where volemic reposition with SS was administered, when comparing it to the group where PHN was used. The HRV research showed that the physiological response of the autonomic nervous system in the PHN group... (Complete abstract click electronic access below) / Doutor