This research develops spatial-explicit methods to characterize the relationship between wildlife and habitat use and selection. Both home range analysis and resource selection function (RSF) models, two common methods of representing wildlife-habitat associations, are often summarized aspatially. I apply a novel method to home range analysis which quantifies the spatial-temporal patterns of site fidelity and range drift. As a result, the spatial structure of home ranges is described, thus building on current methods which summarize ranges as aspatial metrics, often mean area. Furthermore, I develop a new method to spatially assess the ability of RSF models to predict wildlife occurrence using conditional randomization. As opposed to summarizing RSF model accuracy as a single value, I produce spatially-explicit and mappable outputs. I also demonstrate how this spatial method may be used to improve RSF model results. I apply these two spatial-temporal methods to a case study on adult female grizzly bears (Ursus arctos) in the Northeastern slopes of the Canadian Rockies. Through describing the spatial-temporal pattern of grizzly bear home range change, I determine that offspring status and season impact the size and spatial configuration of a bear’s home range. By spatially evaluating the predictive success of a RSF model, I locate and quantify the spatial pattern of areas where the model is under-predicting bear occurrence using Local Moran’s I. Further, I evaluate landscape characteristics at these locations and suggest additions to the model which may increase accuracy. Both home range analysis methods and RSF evaluation techniques could assist in conservation by aiding in the delineation of critical grizzly bear habitat areas in both space and time.