Rocker profiles are one of the most commonly prescribed footwear modifications provided to individuals with impaired rollover. Impaired rollover is caused due to loss of neuromuscular function (i.e. stoke) or orthotic ankle constraint. When rollover is impaired, continued forward progression is interrupted and walking gait becomes less efficient (i.e. increased energy expenditure). Rocker profile footwear modifications are designed to mimic the functions of the anatomical ankle-foot rockers and provide its users with a smooth and efficient rollover. However, while there is theory governing the design of a rocker profile and subjective descriptions of rocker profile function, the extent to which a rocker profile footwear provides rollover has not yet been quantified. The aim of this study was to quantify effective and ineffective rollover and test whether our rocker profile provides effective rollover. We hypothesized that healthy subjects (n=4) walking with orthotic ankle constraint and the rocker profile (STOP) would have no change in rollover and energy expenditure outputs compared to walking with orthotic ankle free and rocker profile (FREE); but that healthy subjects (n=4) walking in STOP would have a change in rollover and energy expenditure outputs compared to walking with orthotic ankle constraint and no rocker profile (STOP-NR). To test this hypothesis, rollover was quantified as stance phase duration, cadence and radius of curvature and energy expenditure was quantified as heart rate and rating of perceived exertion. In addition to these outputs, we analyzed the ground reaction forces and duration of stance in early, middle and late stance period to determine the effects of the rocker profile footwear components. Through the rollover and energy expenditure outputs of the STOP, FREE and STOP-NR conditions, we quantified effective rollover as 0.29 (0.01) radius of curvature with a heart rate of 110.5(6.7) bpm and ineffective rollover as 0.69(0.12) radius of curvature with a heart rate of 131.5 (8.1) bpm. By creating this scale, we were able to determine that our rocker profile provided effective rollover (0.34[0.04] radius of curvature with a heart rate of 111.3[8.3] bpm). However, a future study with a greater sample size is needed to confirm these results.

This thesis is focused on the front and rear suspension of the off-road buggy. For the front suspension is compared the concept with and without pushrod with respect to the kinematics parameters and the damping parameters. For the rear axle, there are three concepts that is compared, especially multilink suspension, double wishbone, and swing axle. Finally, structural design and dimensioning for front axle is performed.

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Diploma thesis deals with the dynamic analysis of OHV pushrod valve train drive of the old-new conception of 6-cylinder tractor engine with 24 valves made by Zetor Tractors, a.s.. There is a requirement to create an analytical model and design valve springs for the engine. The work also points to the current analytical methods of appropriate simulation software used in automotive industry.

Trombocyttransfusion är en viktig behandlingsmetod för att antingen förebygga eller förhindra blödning. Trombocyter för transfusion (trombocytkoncentrat) framställs med två metoder: antingen genom aferesteknik eller genom att separera helblodet i erytrocytenhet, plasma, leukocytenhet och interim platelet unit (IPU). Sedan placeras IPU-enheter på en agitationsmetod. Efter det framställs trombocytkoncentrat genom att poola 4–6 IPU  tillsammans med platelet additive solution (PAS). Syftet med denna studie var att undersöka en ny agitationsmetod för framställning av trombocytkoncentrat, Trombomixer 307, och jämföra den med nuvarande agitationsmetoden, trombocytvagga. Dessutom att undersöka om införandet av Trombomixer 307 kan minska antal IPU-enheter som har  trombocytaggregat. Studien utfördes genom att placerade 100 IPU-enheter på trombocytvagga och 100 placerades på Trombomixer 307. Dessutom framställdes totalt 56 trombocytkoncentrat (28 från Trombomixer 307 och 28 från trombocytvagga) som sedan undersöktes genom kvalitetskontroll av platelet yield index-summa (PYI-värde), volymen, leukocytpartikalkoncentration (LPK) och trombocytpartikalkoncentration (TPK). Resultaten visade att 31 av de 100 IPU-enheterna på Trombomixer 307 hade trombocytaggregat, medan 47 av de 100 IPU-enheter från trombocytvagga hade trombocytaggregat. IPU-enheter på Trombomixer hade en signifikant färre antal IPU-enheter som hade trombocytaggregat jämfört med IPU-enheter från trombocytvagga (p = 0,029). Dessutom visade resultateten att trombocytkoncentrat från Trombomixer hade lägre LPK- och TPK-värde jämfört med trombocytkoncentrat från trombocytvagga. Trombocytkoncentrat från trombocytvagga visade bättre korrelation mellan PYI-summa och TPK-värde. Slutsatsen är att Trombomixer 307 uppfyller krav som en agitationsmetod för framställning av trombocytkoncentrat och att Trombomixer 307 minskar andelen  IPU-enheter som har bildat trombocytaggregat. Dock leder trombocytvagga till bättre kvalitet av trombocytkoncentrat. / Platelet transfusion is a treatment to prevent or stop bleeding. Platelets for transfusion (platelet-concentrate) are produced by separating the blood into erythrocyte-unit, plasma, leukocyte-unit, and interim platelet-unit (IPU). The IPUs are then placed on an agitation method. Platelet-concentrate is prepared by pooling 4–6 IPUs with platelet additive solution (PAS). The purpose of this study was to examine Trombomixer 307 as new agitation method for producing platelet-concentrate, and compare it with the current agitation method, the platelet-rocker. It is also investigated whether the implantation of the Trombomixer 307 can reduce the number of aggregated IPUs. The study was performed by placing 100 IPUs on the platelet-rocker and 100 IPUs on the Trombomixer 307. Additionally, 56 platelet-concentrates were prepared (28 from the Trombomixer 307 and 28 from the platelet-rocker), which then examined through quality control of the platelet yield index sum (PYI value), volume, leukocyte particle concentration (LPK) and platelet particle concentration (TPK). The results showed that 31 out of the 100 IPUs from Trombomixer and 47 of the 100 IPUs from the platelet-rocker were aggregated. IPUs from the Trombomixer had a significantly lower number of aggreged IPUs compared to IPUs from the platelet rocker (p = 0.029). The results also showed that platelet-concentrate from Trombomixer had lower LPK and TPK, while Platelet-concentrate from platelet-rocker showed better correlation between PYI sum and TPK. In conclusion, Trombomixer 307 fulfills requirements as an agitation method to produce platelet-concentrates and reduces the percentage of aggregated IPUs. However, platelet-rocker leads to better quality of platelet-concentrate.

The well known synthesis problem of obtaining dimensions of a four-link mechanism such that a point on the coupler link traces a desired path has been extensively studied. There are two types of path generation–path specified by a finite number of precision points where the prescribed points must be exactly traced, and continuous path generation where the path is approximately traced by the coupler point. In various application, more than one or multiple paths are required to be traced by the coupler point and in such cases, adjustable four-link mechanisms where one of the dimension or parameters of the mechanism can be changed is a possible solution. This thesis deals with the synthesis of planar and spherical adjustable four-link crank-rocker type mechanisms for multiple continuous path generation. Approximate multiple path generation is typically solved as an optimization problem where the dimensions and parameters of the four-link mechanism are obtained such that the objective functions, typically in terms of an error between the desired and obtained path, is minimized. In this thesis, we present a two-stage optimization to obtain four-link mechanism dimensions such that the adjustable four-link mechanism can approximately trace multiple desired paths. In the first stage, the parameters in the driving side of the four-link mechanism is obtained and in the second stage, the parameters of the driven side are obtained. In case of adjustable planar four-link mechanism, a novel optimization objective function based on circle-fitting is used and for spherical adjustable mechanisms a novel plane-fitting based objective function is used. The use of these objective functions results in a lesser number of variables to be searched and thus the method presented in this work is more efficient than existing optimization based algorithms available in literature. Several examples are presented for synthesis of adjustable planar and spherical four-link mechanism for tracing multiple paths. In particular, a spherical mechanism which can generate an oval and an‘ 8’shaped path by one single adjustment is synthesized. This mechanism has been made using 3D printing and it is shown that the mechanism indeed traces the desired oval and ‘8’ shaped paths. This mechanism is being planned for use in a flapping wing micro air vehicle where the oval shaped path is known to make the vehicle to move forward while the ‘8’ shaped path results in a hovering motion.

The diploma thesis involves the design of certification static strength tests for the newly developed aircraft of the TL-Ultralight company. At the beginning of the work, the theory of aircraft testing is generally discussed with emphasis on static strength tests. Furthermore, an analysis of the requirements of the Czech regulation UL 2 and the German LTF-UL, which represent the certification basis for this aircraft, is performed. The requirements of regulations on the construction of the aircraft (or its individual parts) and the requirements for strength tests are discussed in detail. Based on the regulation and the provided calculation protocols, individual test cases and test plans of the wing, tail surfaces, engine bed, and chassis are calculated and prepared. In the end, the calculation of the rocker system and the basic design of jigs are performed.