Reading from paper-based materials has been a major way for people to acquire knowledge. However, paper-based materials are constricted in presenting abstract and complex knowledge or concepts. Recent development of smartphone makes it a device not only for interpersonal communication, but also for accessing rich digital resources over the Internet. Because both paper-based materials and smartphone are mobile and portable, we can make use of the networking capability of smartphone to access digital materials from the Internet to enrich conventional paper-based reading activities such that students¡¦ reading comprehension can be enhanced. The present study came up with an innovative paper-based reading system integrated with digital materials delivered from the smartphone. QR codes were employed to automatically link the content of the print material with relevant digital resources. Also, questions were given to students along the reading process to scaffold the reading activity in order to help students comprehend the essence of the reading pieces. A quasi-experimental design was used to evaluate the effectiveness of the learning system in improving students¡¦ reading comprehension. The results suggested that whether or not using QR code to automate linking digital and print materials does not significantly influence student reading comprehension; however, using questions to scaffold the reading process significantly improves students¡¦ reading comprehension. The survey conducted in the experiment suggested that most of the students agreed that the integrated learning system benefits English reading comprehension. The implication of the results and suggestions to system design and future studies were then addressed.