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This diploma thesis addresses the issue of tiredness. I analyze tiredness from the point of view as the problem that may occur during the teaching process. The theoretical part is focused on the explanation of the concept of psychohygiene, from its historical development to the modern concept, i.e. mental health, tiredness, types of tiredness, its stages and determinants, the specification of the period of adolescence, the influence of environment on the individual. The part of the research addresses the root causes of student´s tiredness. It focuses on the subjective feeling of the perceptions of tiredness with regard to the day of the week, time, the environment of the high school, the influence of natural stimulants.