The objective of this research is to discuss the scientific story intergrated in science curriculum about the students¡¦ attitude towards science and conceptions of the nature of science . This research made use of the Static-group comparison design method for use in quasi-experimental research. The first step was to collect the related scientific background and a scientists¡¦ information, and then create a fictitious story according to the situation in an experimental teaching process, and finally issue a questionnaire in order to understand the students¡¦ experience and conviction. Our research samples were 4 grade 5 classes from a school in Kaohsiung, selected as our test group. Our control groups were 5 classes chosen from another school in Kaohsiung City. We made use of both quantitative and qualitative analysis to collect the data and analyze the information, and the research included the original Questionnaire on the nature of science, Questionnaire on learning science, and an interview information sheet. The questionnaire on the nature of science was analyzed using descriptive statistics and the t-test to obtain a quantitative analysis. The questionnaire on learning science uses percentiles and inductive analysis to obtain a quantitative analysis, with an interview providing qualitative information. The research results indicated that the students enjoyed the fictitious story curriculum, and especially enjoyed hearing about the scientists¡¦ background, as the students believed the stories could assist them in their learning. The students¡¦ attitudes were found to be positive, as the stories were thought to assist them in their learning. Thus, the students were highly interested in the curriculum, though the attitude towards the image of the scientists was not as positive, as was their attitude towards science career planning. On the point of the nature of science, students in the test group were modern minded, and the test group achieved more than the control group. On the quantity and quality of the students¡¦ knowledge, there were significant differences between the test group and the control group. Therefore, the recommendation of this research is that teachers, if interested in this teaching approach, should attempt to collect information on the scientists and their backgrounds. Also, the history of science should be taught to training teachers during their teaching training program. This will assist the teacher in becoming an effective aid towards the students learning of science.