A robust servo control system based on Integral Variable Structure Model Following Control (IVSMFC) is proposed. The IVSMFC approach comprises a reference model part for specifying the design requirements and an Integral Variable Structure Control (IVSC) part for minimizing the errors between the plant and the model. Sliding mode thus obtained features robustness against external disturbances and parameter variations. Design procedures in both continuous-time and discrete-time have been detailed. The IVSMFC-based servo control system has been successfully applied to a DSP-based brushless DC motor drive for globoidal cam indexing system and to power system. Simulation and experimental results demonstrate that the proposed scheme can achieve fast and robust responses.