The current study was designed to test the effectiveness of spinal cord stimulation (SCS) in a retrospective group of 43 failed back surgery syndrome (FBSS) patients. A medical record review was conducted on study participants to capture · relevant presurgical biopsychosocial variables deemed to be of potential prognostic value. In addition, a multidimensional approach to outcome assessment was undertaken along three general domains: general health status, disease specific outcomes, and surgical outcomes. Descriptive statistics of presurgical variables and outcome measurements are provided as well as a model of outcome prediction based on these prognostic variables. Results suggest that the use of neurostimulation may help to reduce low back and/or leg pain in some patients with FBSS; however, a large number of patients reported continuing pain, physical disability, and inability to work despite treatment. The current study calls into question the efficacy of SCS for FBSS. Recommendations for future studies are presented.