Global ETD Search

1	The Stomatin STO-6 is a Novel Regulator of the Caenorhabditis elegans Motor Circuit Barbier, Louis Wei-Chun 15 November 2013 (has links) The ability to move is essential to an animal’s ability to interact with and respond to its changing environment. The nematode Caenorhabditis elegans is a commonly used organism in the study of the genetic and neural bases of behaviours, yet the mechanistic explanation for its ability to move in a smooth sinusoidal wave remains elusive. Here, I present studies of an uncharacterized gene, sto-6, encoding a stomatin protein that regulates C. elegans motor behaviour. I show that this gene plays a role in two unexplained and fundamental processes to C. elegans locomotion: wave initiation and wave propagation. Furthermore, I examine the genetic interaction between sto-6 and an innexin gene unc-7, providing support for the hypothesis that stomatins regulate gap junction proteins in C. elegans. Together, these studies push forward our understanding of the mechanistic basis of C. elegans locomotion, and open up avenues of further inquiry. c. elegans motor circuit stomatin locomotion nervous system 0369 0307 0317
2	The Stomatin STO-6 is a Novel Regulator of the Caenorhabditis elegans Motor Circuit Barbier, Louis Wei-Chun 15 November 2013 (has links) The ability to move is essential to an animal’s ability to interact with and respond to its changing environment. The nematode Caenorhabditis elegans is a commonly used organism in the study of the genetic and neural bases of behaviours, yet the mechanistic explanation for its ability to move in a smooth sinusoidal wave remains elusive. Here, I present studies of an uncharacterized gene, sto-6, encoding a stomatin protein that regulates C. elegans motor behaviour. I show that this gene plays a role in two unexplained and fundamental processes to C. elegans locomotion: wave initiation and wave propagation. Furthermore, I examine the genetic interaction between sto-6 and an innexin gene unc-7, providing support for the hypothesis that stomatins regulate gap junction proteins in C. elegans. Together, these studies push forward our understanding of the mechanistic basis of C. elegans locomotion, and open up avenues of further inquiry. c. elegans motor circuit stomatin locomotion nervous system 0369 0307 0317
3	ACUTE REGULATION OF GLUT1 FUNCTION: THE ROLE OF DETERGENT-RESISTANT MEMBRANE DOMAINS Rubin, Darrell 23 June 2004 (has links) No description available. Biology, Cell Clone 9 cells plasma membrane sucrose density fractionation lipid raft caveolin-1 azide stomatin glucose transport electron microscopy
4	Characterization of Stomatin Suppressors <i>ssu-1</i> AND <i>ssu-2</i> Carroll, Bryan Thomas 15 July 2005 (has links) No description available. C. elegans Caenorhabditis elegans volatile anesthetic unc-1 unc-24 ssu-1 ssu-2 stomatin sulfotransferase ASJ RMD DVA fls485 sterol

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